Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases

AV Cybulsky - Nature Reviews Nephrology, 2017 - nature.com
reticulum (ER) proteostasis, ER stress and the unfolded protein response (UPR), as well as
ER stress-… of the UPR, including a protein that senses misfolded proteins (namely, inositol-…

Endoplasmic reticulum stress and unfolded protein response in neurodegenerative diseases

R Ghemrawi, M Khair - International journal of molecular sciences, 2020 - mdpi.com
reticulum (ER) is an important organelle involved in protein quality … proteins leads to an ER
stress, followed by an adaptive response via the activation of the unfolded protein response (…

Endoplasmic reticulum stress responses in plants

SH Howell - Annual review of plant biology, 2013 - annualreviews.org
… which sets off the unfolded protein response (UPR). Two … stress sets off the unfolded protein
response (UPR). The UPR is a homeostatic response to lighten the load of unfolded proteins

Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease

EJ Ryu, HP Harding, JM Angelastro… - Journal of …, 2002 - Soc Neuroscience
protein response. Immunoblotting confirmed phosphorylation of the key endoplasmic reticulum
stress … There was a similar response to MPP + and rotenone, but not to other apoptotic …

Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium

M Høyer-Hansen, M Jäättelä - Cell Death & Differentiation, 2007 - nature.com
… ER stress caused by the accumulation of unfolded proteinsprotein response (UPR), which
reduces global protein synthesis and induces the synthesis of chaperones and other proteins

Cellular responses to endoplasmic reticulum stress and apoptosis

VI Rasheva, PM Domingos - Apoptosis, 2009 - Springer
… a form of stress to the cell—ER stress. Several … protein response (UPR), have evolved to
detect the accumulation of misfolded proteins in the ER and activate a cellular response that …

Severe injury is associated with insulin resistance, endoplasmic reticulum stress response, and unfolded protein response

MG Jeschke, CC Finnerty, DN Herndon, J Song… - Annals of …, 2012 - journals.lww.com
stress responses are accompanied by profound insulin resistance and hyperglycemia. Genomic
and protein … insulin resistance, ER/sarcoplasmic reticulum stress, inflammation, and cell …

Endoplasmic reticulum stress response and neurodegeneration

W Paschen, T Mengesdorf - Cell calcium, 2005 - Elsevier
… To restore ER functioning, specific stress responses are activated one of which is the unfolded
protein response (UPR). UPR is characterized by a shutdown of global protein synthesis …

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

S Schuck, WA Prinz, KS Thorn, C Voss… - Journal of Cell Biology, 2009 - rupress.org
… In this study, we examine endoplasmic reticulum (ER) membrane expansion during the
unfolded protein response (UPR) in the yeast Saccharomyces cerevisiae. We find that …

The role of endoplasmic reticulum stress and unfolded protein response in atherosclerosis

EA Ivanova, AN Orekhov - International journal of molecular sciences, 2016 - mdpi.com
reticulum stress response is regulated by several signaling mechanisms that involve protein
… In this review we will discuss the role of endoplasmic reticulum stress and apoptosis in …