Characterization of PTEN mutations in brain cancer reveals that pten mono-ubiquitination promotes protein stability and nuclear localization
JRM Yang, P Schiapparelli, HN Nguyen, A Igarashi… - Oncogene, 2017 - nature.com
… protein stability and nuclear localization of mutant PTEN. Thus, our findings provide a
molecular mechanism for cancer-associated PTEN defects and may lead to a brain cancer …
molecular mechanism for cancer-associated PTEN defects and may lead to a brain cancer …
Glycosylation changes in brain cancer
L Veillon, C Fakih, H Abou-El-Hassan… - ACS chemical …, 2018 - ACS Publications
… of protein conformation, stability, and turnover. The focus of this Review is the discussion of
aberrant glycosylation related to brain cancer. … and progression of brain cancer. Additionally, …
aberrant glycosylation related to brain cancer. … and progression of brain cancer. Additionally, …
A glance of p53 functions in brain development, neural stem cells, and brain cancer
Y Xiong, Y Zhang, S Xiong, AE Williams-Villalobo - Biology, 2020 - mdpi.com
… role of p53 in brain development, neural … in brain tumors, especially glioblastomas. Mechanisms
underlying p53 inactivation in brain tumor cells include disruption of p53 protein stability, …
underlying p53 inactivation in brain tumor cells include disruption of p53 protein stability, …
Oncoprotein stabilization in brain tumors
SM Hede, V Savov, H Weishaupt, O Sangfelt… - Oncogene, 2014 - nature.com
… cells from becoming brain cancer cells. A major pathway for targeted protein degradation in
… dependent on GSK-3β phosphorylation that normally regulates β-catenin protein stability. …
… dependent on GSK-3β phosphorylation that normally regulates β-catenin protein stability. …
Signaling the unfolded protein response in primary brain cancers
… In glioblastoma (GBM), the highest grade of primary brain cancers, tumor invasion is a mark
of aggressiveness. Interestingly, the extracellular matrix protein SPARC, involved in tumor …
of aggressiveness. Interestingly, the extracellular matrix protein SPARC, involved in tumor …
Inhibition of breast and brain cancer cell growth by BCCIPα, an evolutionarily conserved nuclear protein that interacts with BRCA2
J Liu, Y Yuan, J Huan, Z Shen - Oncogene, 2001 - nature.com
… cancer cell growth by BCCIPα We further expressed HA-tagged BCCIPα protein in a few brain
and breast cancer cell … virus were used to infect brain and breast cancer cell lines, the HA-…
and breast cancer cell … virus were used to infect brain and breast cancer cell lines, the HA-…
The role of inflammation in brain cancer
JL Sowers, KM Johnson, C Conrad, JT Patterson… - … and Cancer, 2014 - Springer
… brain tumors (CBTRUS 2011), they will be the focus of this review on inflammation and brain
cancer. … Protein levels of p53 are regulated by the mouse double minute 2 homolog (MDM2) …
cancer. … Protein levels of p53 are regulated by the mouse double minute 2 homolog (MDM2) …
Physics of brain cancer: Multiscale alterations of glioblastoma cells under extracellular matrix stiffening
… YAP (yes-associated protein) is a protein that acts as a transcriptional regulator by … protein
stability, or a wide range of additional factors. The nuclear softening phenotype of cancer cells …
stability, or a wide range of additional factors. The nuclear softening phenotype of cancer cells …
[HTML][HTML] The biochemical, nanomechanical and chemometric signatures of brain cancer
H Abramczyk, A Imiela - Spectrochimica Acta Part A: Molecular and …, 2018 - Elsevier
… protein contents. We have found that the ratio reflects the lipid and protein contents of
tumorous brain … on the nanomechanical signature of brain cancer. A combination of AFM and …
tumorous brain … on the nanomechanical signature of brain cancer. A combination of AFM and …
Survivin: a target from brain cancer to neurodegenerative disease
… are synthesized in the cytosol and transported into the mitochondria, probably via an N-terminal
motif of precursor proteins and TOM20 and TOM70 receptor proteins located in the …
motif of precursor proteins and TOM20 and TOM70 receptor proteins located in the …
相关搜索
- evolutionarily conserved nuclear protein brain cancer
- protein response primary brain cancers
- mono ubiquitination brain cancer
- glycosylation alterations brain cancer
- glycosylation changes brain cancer
- p53 functions brain cancer
- multiscale alterations brain cancer
- molecular fingerprinting brain cancer
- pharmacological targets brain cancer
- brain cancers neurodegenerative diseases
- role of inflammation brain cancer
- unfolded protein response in cancer
- anti-apoptosis protein implications for cancer
- protein glycosylation gastric and colorectal cancers
- protein response cancer cell fate
- protein response brain tumor cell lines