… with activated tyrosine protein kinases. Here we report that p95", a proto-oncogene product
… domain and is a substrate for tyrosine protein kinases. Exposure of quiescent NIH3T3 cells …

… These results confirmed that the PDGF-induced protein kinase activity associated with the
… the AH/PH mutations did not affect the ability of these proteins to function as protein kinases. …

… The plethora of proto-oncogenes encoding protein kinases with a specificity for tyrosine
does not reflect simple gene duplication. Although the catalytic domains of this class of …

… kinase regulatory pathways through the PI pathway to protein kinase C activity or by acting
through protein kinase … Either of these protein kinases may directly modulate phosphorylation …

… Other similar receptors have been identified with protein kinase activity (table 1) [6]. …
protein kinases are relatively well characterized, their physiologic and pathophysiologic protein …

… a much greater protein kinase activity than c-src and results in cell transformation. In addition
to unregulated kinase activity, transduction of c-srcalso places the proto-oncogene under …

… protein kinase C-catalyzed phosphorylation events within the amino-terminal 200 amino acids.
However, inhibitors of protein kinase C … kinase other than the traditional protein kinase C (…

… the protein kinase Cthe ribosomal protein S6 and activated an S6 protein kinase in the normal
but not in the protein kinase C- … protein kinaseC, but promoted the phospho- such as proto-…

… of protein kinases, which begins with the product of the RAF proto-oncogene and
continues through a mitogen-activated protein-kinase kinase (MAPKK) and a mitogen-activated …

… , imply ing that normal cells too have tyrosine specific protein kinases. The first such
enzyme we identified in a normal cell was none other than the prod uct of the proto-src gene. …