… When grown in divalent cation-limited medium, Pseudomonas aeruginosa becomes …
PmrA-PmrB two-component regulatory systems. To further characterize Mg 2+ regulation in P…

… Pseudomonas aeruginosa PAO1 wild-type and isogenic knockout strains of phoP and pmrA
were … Colistin killing at subinhibitory concentrations was greater against the phoP and pmrA …

… to Salmonella enterica, in which a prototypical resistance-conferring mutation occurred in
the cognate response regulator PmrA (50), the few PmrA mutations that we have found in P. …

… Pseudomonas aeruginosa were isolated from clinical samples ie wound, blood and urine.
The maximum number of Pseudomonas aeruginosa … ) did harbor the PmrA and PmrB genes, …

… while expression of the response regulator pmrA in trans resulted in … pmrA‐pmrB operon
is autoregulated. Interposon mutants in pmrB, pmrA, or in an intergenic region upstream of pmrA…

… that high-level polymyxin resistance in P. aeruginosa is caused by alterations of both PhoQ
and PmrB. … Although involvement of PhoQ and PmrB in polymyxin B resistance is known in P. …

… of PmrA-PmrB and PhoP-PhoQ in colistin-nonsusceptible P. … found in 17 sites of pmrA gene,
43 sites of pmrB gene, 7 sites … were found in 3 sites of PmrA, 12 sites of PmrB, and 2 sites of …

… Gene replacement was performed to knock out the genes of pmrA and arnB from P. …
numbers of PmrB were used from Pseudomonas aeruginosa PAO1 (http://www.pseudomonas.com). …

… Since the genes phoQ and pmrB are controlled by their upstream genes (oprH and pmrA)
(13, 16), full-length oprH-phoPQ from NY214, NY215, NY217, and NY219 and full-length …

… this operon requires the PmrA–PmrB two-component regulatory system, where PmrB is the
integral membrane sensor kinase that responds to high Fe 3+ levels and PmrA is the cognate …