Pseudomonas putida—a versatile host for the production of natural products

A Loeschcke, S Thies - Applied microbiology and biotechnology, 2015 - Springer
production strains enables biotechnological access to a variety of valuable compounds by
conversion of renewable resources. Pseudomonas putida … an overview of applications of P. …

Convergent Peripheral Pathways Catalyze Initial Glucose Catabolism in Pseudomonas putida: Genomic and Flux Analysis

T Del Castillo, JL Ramos… - Journal of …, 2007 - Am Soc Microbiol
In this study, we show that glucose catabolism in Pseudomonas putida occurs through the
simultaneous operation of three pathways that converge at the level of 6-phosphogluconate, …

Metabolism of syringyl lignin-derived compounds in Pseudomonas putida enables convergent production of 2-pyrone-4, 6-dicarboxylic acid

S Notonier, AZ Werner, E Kuatsjah, L Dumalo… - Metabolic …, 2021 - Elsevier
… (B) Metabolic pathway in Pseudomonas putida KT2440 characterized in this study. Cofactors
and byproducts of key reactions are shown. Dashed lines represent reactions catalyzed by …

Pseudomonas putida and its close relatives: mixing and mastering the perfect tune for plants

SB Costa-Gutierrez, C Adler, M Espinosa-Urgel… - Applied Microbiology …, 2022 - Springer
… Among the various PGPR species, some Pseudomonas putida … the state of the art and the
most relevant findings related to P. … Inoculation of ACC deaminase-producing P putida could …

Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440

GJ Bentley, N Narayanan, RK Jha, D Salvachúa… - Metabolic …, 2020 - Elsevier
Pseudomonas putida KT2440 has received increasing attention as an important biocatalyst
for … P. putida has been previously engineered to produce muconate from glucose; however, …

Production of medium chain length polyhydroxyalkanoate in metabolic flux optimized Pseudomonas putida

JM Borrero-de Acuña, A Bielecka, S Häussler… - Microbial cell …, 2014 - Springer
… To ensure well-controlled mcl-PHA production using our metabolically engineered P. putida
strains, aerobic batch fermentations of the KT2440-acoA and KT2440Δgcd-acoA strains on …

Genome reduction boosts heterologous gene expression in Pseudomonas putida

S Lieder, PI Nikel, V de Lorenzo, R Takors - Microbial cell factories, 2015 - Springer
… In this study, we have assessed the use of two heavily re-factored P. putida strains as
potential hosts for protein production in a bioreactor setup. One of them lacks flagella, while the …

[HTML][HTML] Refactoring the upper sugar metabolism of Pseudomonas putida for co-utilization of cellobiose, xylose, and glucose

P Dvořák, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
… its capacity to tolerate stress, NAD(P)H/ NAD(P) balance, and increased ATP levels, the
platform strain Pseudomonas putida EM42, a genome-edited derivative of the soil bacterium P. …

[HTML][HTML] Pseudomonas putida as a functional chassis for industrial biocatalysis: from native biochemistry to trans-metabolism

PI Nikel, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
… the later in strain KT2440), these pathways converge at the key intermediate 6-phosphogluconate—…
putida has been engineered for the production of aromatic compounds that are often …

Muconic acid production from glucose and xylose in Pseudomonas putida via evolution and metabolic engineering

C Ling, GL Peabody, D Salvachúa, YM Kim… - Nature …, 2022 - nature.com
… In this study, Pseudomonas putida KT2440 is engineered to convert glucose and xylose,
the primary carbohydrates in lignocellulosic hydrolysates, to muconic acid using a model-…