[HTML][HTML] Neuromodulatory treatments for psychiatric disease: a comprehensive survey of the clinical trial landscape

GJB Elias, A Boutet, R Parmar, EHY Wong, J Germann… - Brain Stimulation, 2021 - Elsevier
… a dominant position in this research landscape, being the most … trials. This research focus
may simply reflect the fact that depression is the top cause of mental health-related disease

[PDF][PDF] Contrasting clinical trials in oncology and psychiatry: landscape as proxy for efficiency in drug development

CA van den Bogert, HGM Leufkens - Trials & Tribulations, 2017 - pharmaceuticalpolicy.nl
… of this contrast include the lack of pharmacotherapeutic successes and scientific progress,
disagreement in medicine and society about the nature and treatment of psychiatric diseases, …

Charting the landscape of priority problems in psychiatry, part 1: classification and diagnosis

KE Stephan, DR Bach, PC Fletcher, J Flint… - … Lancet Psychiatry, 2016 - thelancet.com
… not guide treatment, which largely depends on trial and error. The development of therapies
is … If we accept genetics as a way to define psychiatric disease, there could be more similarity …

Pharmacotherapies for treatment-resistant depression: how antipsychotics fit in the rapidly evolving therapeutic landscape

MK Jha, SJ Mathew - American Journal of Psychiatry, 2023 - Am Psychiatric Assoc
… With the rapidly evolving landscape of antidepressant treatments over the past few years, …
Pragmatic clinical trials are needed to compare the effectiveness of atypical antipsychotics …

The changing landscape of randomized clinical trials in cardiovascular disease

WS Jones, MT Roe, EM Antman, MJ Pletcher… - Journal of the American …, 2016 - jacc.org
landscape of cardiovascular clinical trials in the United States, highlight recently conducted
registry-based clinical trials… of the recently launched pragmatic clinical trial by the Patient-…

Botulinum toxin injections for Psychiatric Disorders: A Systematic Review of the Clinical trial landscape

I Demchenko, A Swiderski, H Liu, H Jung, W Lou… - Toxins, 2024 - mdpi.com
… Following screening for eligibility, four unpublished clinical trials in total were included in
this … trials included in this systematic review of botulinum toxin type A therapy for psychiatric

Challenges and opportunities for improving the landscape for Lewy body dementia clinical trials

JG Goldman, LK Forsberg, BF Boeve… - Alzheimer's research & …, 2020 - Springer
… the landscape of LBD clinical trials. This review highlights the formation of the LBDA IAC,
current state of LBD clinical trials, and challenges and opportunities in the field regarding trial

[PDF][PDF] Balancing therapeutic safety and efficacy to improve clinical and economic outcomes in schizophrenia: exploring the treatment landscape

DC Javitt - Am J Manag Care, 2014 - ajmc.s3.amazonaws.com
… to those seen in other trials.Prior to these clinical trials, most practice guidelines unequivocally
… decades, gaps in treatment for the psychiatric disease remain. Great care should be taken …

The case for practical clinical trials in psychiatry

JS March, SG Silva, S Compton… - … of Psychiatry, 2005 - Am Psychiatric Assoc
… and scope of practical clinical trials, give examples of practical clinical trials, and discuss
the … trials model in psychiatry, including issues of funding. RESULTS: Practical clinical trials, …

[HTML][HTML] The current landscape of prevention trials in dementia

J Lee, RS Howard, LS Schneider - Neurotherapeutics, 2023 - Elsevier
… primary, secondary, and tertiary prevention trials for dementia and AD, overall … landscape
of prevention trials. We included 32 pharmacologic intervention trials and 9 multi-domain trials. …