Phosphorylcholine antibodies in pulmonary infection

S Nishinarita, S Sawada, T Horie - Medical microbiology and immunology, 1990 - Springer
… The typical course of anti-PC antibody levels in acute pulmonary infection is shown in Fig.
3A. The patient was diagnosed as having … Phosphorylcholine antibody in pulmonary infection

High anti-phosphorylcholine antibody levels and mortality associated with pneumonia

G Nordenstam, B Andersson, D Brile… - … journal of infectious …, 1990 - Taylor & Francis
… and since anti-polysaccharide antibodies are highly protective against most … of antibodies
to phosphorylcholine. The relationship between the levels of antibodies to phosphorylcholine

Role of Phosphorylcholine-Specific Immunoglobulin M in acute upper respiratory tract infections

J Ohori, T Jimura, Y Kurono - Annals of Otology, Rhinology & …, 2019 - journals.sagepub.com
… Correlation between C-reactive protein (CRP) level and phosphorylcholine (PC)–specific
antibody level. A significant negative correlation was observed between PC-specific …

Cross-reactivity of human immunoglobulin G2 recognizing phosphorylcholine and evidence for protection against major bacterial pathogens of the human respiratory …

HB Goldenberg, TL McCool… - The Journal of infectious …, 2004 - academic.oup.com
… Survival of xid mice after passive immunization with human anti-phosphorylcholine (ChoP)
antibody. Two hours after intraperitoneal (ip) administration of purified human anti-ChoP …

Impaired antibody response to pneumococcal capsular polysaccharides and phosphorylcholine in adult patients with a history of bacteremic pneumococcal infection

K Ekdahl, JH Braconier… - Clinical infectious …, 1997 - academic.oup.com
… undetected IgG subclass deficiencies may result in permanent lung damage [39], we
suggest that all patients with invasive over the reference ranges (table 2). Isolated impaired …

Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases

J Frostegård - Metabolites, 2023 - mdpi.com
Phosphorylcholine (PC) is a small lipid-related antigen, which is both a danger associated
molecular pattern (DAMP), and a pathogen associated molecular pattern (PAMP). Antibodies

Antibodies against phosphorylcholine and protection against atherosclerosis, cardiovascular disease and chronic inflammation

J Frostegård - Expert Review of Clinical Immunology, 2022 - Taylor & Francis
… because much more is known about phosphorylcholine (PC) and antibodies against PC (anti-…
Furthermore, IgM anti-PC is associated with protection against upper respiratory infections[…

Role of phosphorylcholine in Streptococcus pneumoniae and nontypeable Haemophilus influenzae adherence to epithelial cells

H Iuchi, J Ohori, T Kyutoku, K Ito, Y Kurono - Auris Nasus Larynx, 2019 - Elsevier
antibody against PC can protect mice from lethal infection with mouse-virulent human Spn
isolates [7]. In a mouse model of pulmonary infection … resistance to pulmonary clearance, and …

Novel Phosphorylcholine-Containing Protein of Pseudomonas aeruginosa Chronic Infection Isolates Interacts with Airway Epithelial Cells

M Barbier, A Oliver, J Rao, SL Hanna… - … Journal of infectious …, 2008 - academic.oup.com
phosphorylcholine (ChoP) epitope, a structure crucial for the virulence of several respiratory
infections revealed that expression of ChoP at 37C was higher among strains from chronic …

Microbial modulation of host immunity with the small molecule phosphorylcholine

SE Clark, JN Weiser - Infection and immunity, 2013 - Am Soc Microbiol
… influenzae strains expressing ChoP also have delayed clearance from the lungs of
infected … affinity than antibodies induced following infection (96). The major idiotype of anti-ChoP …