Pathophysiological characteristics and therapeutic approaches for pulmonary injury and cardiovascular complications of coronavirus disease 2019

YJ Geng, ZY Wei, HY Qian, J Huang, R Lodato… - Cardiovascular …, 2020 - Elsevier
… primary pulmonary injury and subsequent cardiovascular complications constitute the key
pathophysiology of this deadly disease. … of pulmonary and cardiovascular injury of COVID-19. …

Long-term pulmonary consequences of coronavirus disease 2019 (COVID-19): what we know and what to expect

S Salehi, S Reddy… - Journal of thoracic …, 2020 - journals.lww.com
pulmonary injury gradually decreased, but the findings were not completely resolved. The
evolution and healing of the pulmonary disease … in 2003, the pulmonary function in 2018 was …

[HTML][HTML] An update on pulmonary hypertension in coronavirus disease-19 (COVID-19)

AK Mishra, A Lal, KK Sahu, AA George… - Acta Bio Medica …, 2020 - ncbi.nlm.nih.gov
… with chronic obstructive pulmonary disease, and heart … injury in patients with COVID-19,
have consistently shown that patients with severe myocardial injury, have higher pulmonary

Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase

Y Huang, C Tan, J Wu, M Chen, Z Wang, L Luo… - Respiratory …, 2020 - Springer
… to the degree of lung injury and rehabilitation in patients with COVID-19. Retrospective … , a
few patients even had pulmonary fibrosis. Lung function damage of patients with COVID-19 in …

Vascular endothelial injury exacerbates coronavirus disease 2019: The role of endothelial glycocalyx protection

H Okada, S Yoshida, A Hara, S Ogura… - …, 2021 - Wiley Online Library
… A very recent report revealed that recombinant human thrombomodulin (rhTM) protects
endothelial glycocalyx from lipopolysaccharide (LPS)-induced pulmonary injury. This mechanism …

Pulmonary vascular inflammation with fatal coronavirus disease 2019 (COVID-19): possible role for the NLRP3 inflammasome

O Paul, JQ Tao, E West, L Litzky, M Feldman… - Respiratory …, 2022 - Springer
… inflammation and injury with COVID-19 (such as immune cell aggregation and extravasation,
edema, formation of thrombi and leukopenia) possibly lies in pulmonary endothelial …

[HTML][HTML] Pulmonary vascular endothelial injury and acute pulmonary hypertension caused by COVID-19: the fundamental cause of refractory hypoxemia?

X Wang, Y Tu, B Huang, Y Li, Y Li, S Zhang… - Cardiovascular …, 2020 - ncbi.nlm.nih.gov
… , pulmonary vascular remodeling, and pulmonary fibrosis due … pulmonary vessels into alveoli
would aggravate pulmonary … treatment of pulmonary vascular endothelium in COVID-19, …

The emerging spectrum of cardiopulmonary pathology of the coronavirus disease 2019 (COVID-19): Report of 3 autopsies from Houston, Texas, and review of autopsy …

LM Buja, DA Wolf, B Zhao, B Akkanti… - Cardiovascular …, 2020 - Elsevier
… that COVID-19 is a systemic disease with major pulmonary and cardiac manifestations. …
pathogenesis of severe COVID-19 disease involves direct viral-induced injury of multiple organs, …

Effect of Coronavirus Disease 2019 in Pulmonary Circulation. The particular scenario of precapillary pulmonary hypertension

J Nuche, T Segura de la Cal, C Jiménez López Guarch… - Diagnostics, 2020 - mdpi.com
The Coronavirus Disease of 2019 (COVID-19) has supposed a global health emergency …
disease. Patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic …

Lung transplantation as therapeutic option in acute respiratory distress syndrome for coronavirus disease 2019-related pulmonary fibrosis

JY Chen, K Qiao, F Liu, B Wu, X Xu, GQ Jiao… - Chinese medical …, 2020 - mednexus.org
… national guidelines for COVID-19,[8] we observed a more severe pulmonary injury [Table
2]. Generally, extensive hemorrhage and fibrosis occurs in patients with end-stage ARDS post-…