… in the F344 rat using the inhibition of carcinogen-induced aberrant crypt foci (ACF) in the colon
as … specificity and sensitivity in predicting which agents are likely to prevent colon cancer. …

… in rats treated with the colon carcinogen 1,2-dimethylhydrazine (DMH). In addition, DNA
damage in colon … to determine the effect of annatto on DMH-induced rat colon carcinogenesis. …

… reduction of several biomarkers of colon cancer by dietary … ity observed in vitro in HT-29
colon cancer cell line studies (5,6). … in human colonic mucosa: putative preneoplastic lesions. J …

… Abstract Deaths from colon cancer number over 60,000 … cause of cancerrelated mortality,
with over 60,00() … early detection, colorectal cancer has a high cure rate (3, 4). However, …

… colonocytes, as a sensitive technique for detecting diagnostic colonic biomarkers. In this
study, we used the rat colon carcinogenesis model to determine if changes in fecal protein …

… descending colon of humans (1) and in carcinogen treated rats (2-… ACF/rat will increase or
decrease the risk for colon cancer. This … This study of archived rat colon tissue collected after a …

… stem cell biomarker. In this review we discuss the candidate colonic stem cell biomarkers
which … Furthermore, we investigate the putative biomarkers for so-called colorectal cancer stem …

… 6C), a putative stem-cell biomarker, was significantly higher in the crypts of Pirc rats
compared with those of wt rats, and also, higher in younger than in older animals. The pan-…

… cancer agents. The overall aim with this thesis was to further characterize a selection of
early/intermediate biomarkers and to assess the colon cancer … three selected biomarkers differed …

… could be used as a biomarker of colon carcinogenesis to evaluate tumor … putative preneoplastic
lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis…