… buccal film of clonidine hydrochloride by employing quality by design (QbD) based approach…
The total nine formulations were prepared according to formulation by design helped by …

… The main aim of the present work was to develop a mucoadhesive buccal film by applying
the QbD approach. GLB belongs to BCS class II drugs (Low solubility, High permeability). The …

… on the development of buccal films with … a Quality by Design (Qbd) approach. Utilizing
hot-melt extrusion technology, we aimed to fabricate films aligned with the patient-centered quality …

… Mucoadhesive buccal films have … buccal films by relying on quality-by-design (QbD)
principles. Previous knowledge and experience were employed to firstly identify the critical quality …

… a fast-dissolving buccal film of the BCS Class I anti-anginal drug Ivabradine hydrochloride
using the Quality by Design (QbD) approach. QbD is a systematic method that starts with …

… It does not only impart the necessary mechanical properties to the oral film, but also
influences the release of the active ingredient into the oral cavity through disintegration. It is …

… The ex vivo buccal permeation of REP from the buccal tablet via the porcine buccal mucosa
was studied on Franz-diffusion cell. Freshly collected buccal mucosa was mounted between …

… mg/cm2) in the mechanical properties of buccal films. Methods: A quality by design (QbD)
approach based on a full factorial design (3 x 23) and complementarily multivariate statistical …

… Oral bioavailability is the main decisive factor in achieving the desired … quality-by-design
(QbD) approach to develop and optimize the therapeutically efficient instant release buccal films …

… The quality by design (QbD) approach was applied for optimizing the formulation of
extemporaneously prepared orodispersible films (ODFs) using Design-Expert® Software. The …