… events (SAEs) in COPD patients. Since the risk of combining a LABA with a LAMA could be
greater, we have carried out a quantitative synthesis to investigate the cardiovascular safety …

… The ICS being successfully used for reducing the mortality … performing an exhaustive
quantitative synthesis, stratified by … density in the quantitative synthesis of prospective controlled …

… than conventional measures, and the occurrence of clinical outcomes including exacerbations,
hospitalisation and mortality within a COPD population. Individual studies and a limited …

… prevented assessment of risk of bias and quantitative synthesis of results ( Figure 1 ). Detailed
characteristics of the studies included are presented in Table 1 and in Tables S3 and S4. …

… ) can predict increased mortality in hospitalized COPD patients is still … between CAP and
mortality and morbidity in COPD patients hospitalized … Studies included in quantitative synthesis …

… mortality? Half of those patients hospitalized will be readmitted at least once over the next 6
months, a Chronic obstructive pulmonary disease … symptoms, reduce COPD exacerbations, …

… of chronic obstructive pulmonary disease and overall mortality … chronic obstructive pulmonary
disease should be designed to include both efficacy and cardiovascular disease mortality (…

… Quantitative data synthesis The meta-analysis results of the associations between mortality
rates and … It is not surprising that COPD was a poor prognosis of COVID-19, considering that …

… reached by the 2 reviewers on the eligible references to be included for further synthesis
and analysis. … We retained 13 trials that met the inclusion criteria for quantitative meta-analysis. …

… of interest (mortality, acute episode of COPD, hospitalization, or cardio-cerebrovascular
events) and had to enroll a minimum of 100 participants. In quantitative synthesis analysis, the …