2-substituted quinoline alkaloids as potential antileishmanial drugs
A Fournet, AA Barrios, V Muñoz… - Antimicrobial agents …, 1993 - Am Soc Microbiol
… tuted quinoline alkaloids. The aims of this study were to evaluate and demonstrate the
activities of these quinoline alkaloids in BALB/c mice infected with New World strains causing …
activities of these quinoline alkaloids in BALB/c mice infected with New World strains causing …
Antileishmanial activity of synthetic analogs of the naturally occurring quinolone alkaloid N-methyl-8-methoxyflindersin
… Quinoline alkaloids, secondary metabolites found in plants from the … synthetic quinoline
alkaloids having structure similar to that of compound 1 and then tested these quinoline alkaloids …
alkaloids having structure similar to that of compound 1 and then tested these quinoline alkaloids …
Fighting against Leishmaniasis: search of alkaloids as future true potential anti-Leishmanial agents
… derived alkaloids in view of their antileishmanial potentials. This review is focused to cover
… ) quinoline (50) are also found to be active. Subcutaneous treatment with quinoline alkaloids …
… ) quinoline (50) are also found to be active. Subcutaneous treatment with quinoline alkaloids …
The potential of 2-substituted quinolines as antileishmanial drug candidates
PM Loiseau, K Balaraman, G Barratt, S Pomel… - Molecules, 2022 - mdpi.com
… This study was the first to demonstrate the activity of 2-substituted quinoline alkaloids in the
experimental treatment of visceral leishmaniasis. Another study in the same model showed …
experimental treatment of visceral leishmaniasis. Another study in the same model showed …
Antileishmanial potential of alkaloids isolated from plants: an integrative review
ASS da Veiga, HPC Brígido, S Percário… - Research, Society and …, 2020 - rsdjournal.org
… Leishmaniasis treatment is often carried out with drugs of high toxic potential and high
cost, … About the antileishmanial activity of β-carbolinic alkaloids, there is a lack of studies to …
cost, … About the antileishmanial activity of β-carbolinic alkaloids, there is a lack of studies to …
Quinoline alkaloids against neglected tropical diseases
… The Galipea genus is abundant in the simple mono- or disubstituted quinoline alkaloids that
have a potent antileishmanial activity [64-66]. These plants were traditionally used by native …
have a potent antileishmanial activity [64-66]. These plants were traditionally used by native …
Antiprotozoal activity of quinoline alkaloids isolated from Galipea longiflora, a Bolivian plant used as a treatment for cutaneous leishmaniasis
A Fournet, AA Barrios, V Muñoz… - Phytotherapy …, 1994 - Wiley Online Library
… This work describes the in uitro antileishmanial and trypanocidal activities of the 12
quinolines alkaloids and the in uiuo activity of two major alkaloids of Galipea longiflora, 2-…
quinolines alkaloids and the in uiuo activity of two major alkaloids of Galipea longiflora, 2-…
Alkaloids: future prospective to combat leishmaniasis
… Many of alkaloids are reported to have excellent antileishmanial … derived alkaloids in view
of their antileishmanial potentials. … Two more quinoline alkaloids namely dictylomide A (9) and …
of their antileishmanial potentials. … Two more quinoline alkaloids namely dictylomide A (9) and …
Interactions of Antiparasitic Alkaloids with Leishmania Protein Targets: A Molecular Docking Analysis
… potential binding partners of antileishmanial alkaloids; molecular docking analyses have been
carried out with many of the established Leishmania protein drug … quinoline alkaloids that …
carried out with many of the established Leishmania protein drug … quinoline alkaloids that …
Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents
A Tejeria, Y Perez-Pertejo, RM Reguera… - European journal of …, 2019 - Elsevier
… Liposomal AmB (AmBisome, Gilead) is an effective antileishmanial medicine but has some
drawbacks; it requires slow intravenous administration, is costly and chemically unstable …
drawbacks; it requires slow intravenous administration, is costly and chemically unstable …
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