… characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD (P) H: quinone oxidoreductase1 gene

S Dhakshinamoorthy, AK Jaiswal - Oncogene, 2001 - nature.com
Antioxidant response element (ARE) and nuclear … and other detoxifying enzyme genes in
response to antioxidants and … Treatment of cells with antioxidants and xenobiotics results in the …

A review of NAD (P) H: Quinone oxidoreductase 1 (NQO1); A multifunctional antioxidant enzyme

A Atia, N Alrawaiq, A Abdullah - Journal of Applied Pharmaceutical …, 2014 - japsonline.com
… -induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows
Nrf2 to bind to the antioxidant response element and activate defensive gene expression. J …

Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD (P) H: quinone oxidoreductase1 gene

K Sankaranarayanan, AK Jaiswal - Journal of Biological Chemistry, 2004 - ASBMB
… Nrf3 in ARE-mediated gene expression and induction of NQO1 in response to antioxidants.
… and endogenous NQO1 gene expression and induction in response to antioxidant tert-…

Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD (P) H: quinone oxidoreductase 1 gene: reassessment of the ARE …

P Nioi, M McMahon, K Itoh, M Yamamoto… - Biochemical …, 2003 - portlandpress.com
… NQO1 [NAD(P)H:quinone oxidoreductase 1] has an integral role in cellular responses to …
show that Nrf2 regulates this gene directly via an ARE (antioxidant response element) that lies …

… MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD (P) H: Quinone oxidoreductase1 gene

S Dhakshinamoorthy, AK Jaiswal - Journal of Biological Chemistry, 2000 - ASBMB
… NAD(P)H:quinone oxidoreductase1 (NQO1) 1 is a flavoprotein that catalyzes two-electron
reductive metabolism and detoxification of quinones. This protects cells against quinone-…

… Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1gene

R Venugopal, AK Jaiswal - Proceedings of the National …, 1996 - National Acad Sciences
… Twenty-four base pairs of the human antioxidant response element (hARE) are … :quinone
oxidoreductase 1 (NQO 1 ) gene and its induction in response to xenobiotics and antioxidants. …

… regulation of the antioxidant response element (ARE)-mediated NAD (P) H: quinone oxidoreductase 1 gene expression and induction in response to antioxidants

S Dhakshinamoorthy, AK Jain, DA Bloom… - Journal of Biological …, 2005 - ASBMB
… the expression and coordinated induction of genes encoding detoxifying enzymes including
NAD(P)H:quinone oxidoreductase1 (NQO1) in response to antioxidants. In this report, we …

NAD (P) H: quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms

D Ross, JK Kepa, SL Winski, HD Beall, A Anwar… - Chemico-biological …, 2000 - Elsevier
… and its role in antioxidant defense via the generation of antioxidant forms of ubiquinone …
gene regulation and the role of the antioxidant response element and the xenobiotic response

NAD(P)H:Quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues

M Belinsky, AK Jaiswal - Cancer and Metastasis Reviews, 1993 - Springer
… The high level of expression of the NQO1 gene and its … Antioxidant Response Element
(hARE) and are mediated by products of proto-oncogenes, Jun and Fos. Induction of NQO 1 gene

Antioxidant response element-mediated 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) induction of human NAD (P) H: quinone oxidoreductase 1 gene expression

V Radjendirane, AK Jaiswal - Biochemical pharmacology, 1999 - Elsevier
Antioxidant response element (ARE) is required for … :quinone oxidoreductase 1 (NQO1)
gene in tumor cells and its induction in response to β-naphthoflavone and phenolic antioxidants. …