Quorumsensing system in Acinetobacter baumannii: a potential target for new drug development

K Saipriya, CH Swathi, KS Ratnakar… - Journal of applied …, 2020 - academic.oup.com
Acinetobacter baumannii causes several nosocomial infections and poses major threat
when it is multidrug resistant. Even pan drug‐resistant strains have been reported in some …

Quorum Sensing Inhibition or Quenching in Acinetobacter baumannii: The Novel Therapeutic Strategies for New Drug Development

S Zhong, S He - Frontiers in Microbiology, 2021 - frontiersin.org
baumannii clinical isolates to common … called quorum sensing (QS). In contrast, the two
main approaches of QS interference, quorum sensing inhibitors (QSIs) and quorum quenching (…

Quorum sensing in Acinetobacter: an emerging pathogen

N Bhargava, P Sharma, N Capalash - Critical reviews in …, 2010 - Taylor & Francis
… indicate that Acinetobacter baumannii is closely related to Burkholderia ambifaria but its
quorum sensing genes (… The prospects of quorum quenching to control the infections caused by …

Quorum sensing network in clinical strains of A. baumannii: AidA is a new quorum quenching enzyme

…, L Blasco, A Muras, FM Ruiz, G Bou, A Otero… - PloS one, 2017 - journals.plos.org
… assays (microarrays and RT-PCR) to analyze the Quorum Sensing/Quenching systems in
clinical strains of Acinetobacter baumannii in relation to surface motility. We also studied the …

[HTML][HTML] The role of quorum sensing, biofilm formation, and iron acquisition as key virulence mechanisms in Acinetobacter baumannii and the corresponding anti …

SKK Law, HS Tan - Microbiological Research, 2022 - Elsevier
Acinetobacter baumannii is a nosocomial pathogen responsible for several serious infections,
including pneumonia, sepsis, and meningitis. The propensity of this bacterium to rapidly …

AbaM Regulates Quorum Sensing, Biofilm Formation, and Virulence in Acinetobacter baumannii

M López-Martín, JF Dubern, MR Alexander… - Journal of …, 2021 - Am Soc Microbiol
Acinetobacter baumannii possesses a single divergent luxR/luxRI-type quorum-sensing (QS) …
baumannii strain AB5075 resulted in increased production of N-(3-hydroxydodecanoyl)-l-…

Exploiting quorum sensing inhibition for the control of Pseudomonas aeruginosa and Acinetobacter baumannii biofilms

I Castillo-Juarez, LE Lopez-Jacome… - Current Topics in …, 2017 - ingentaconnect.com
… with these quorum-sensingquorum sensing systems of both organisms, the way they
coordinate the formation of biofilms, the recent advances in biofilm disruption by quorum sensing

Contribution of the AbaI/AbaR Quorum Sensing System to Resistance and Virulence of Acinetobacter baumannii Clinical Strains

J Tang, Y Chen, X Wang, Y Ding, X Sun… - Infection and Drug …, 2020 - Taylor & Francis
Background Acinetobacter baumannii (A. baumannii) is one of the most important pathogens
that cause serious nosocomial infections worldwide. However, there are few reports on the …

Quorum Sensing as a Target for Controlling Surface Associated Motility and Biofilm Formation in Acinetobacter baumannii ATCC® 17978TM

C Mayer, A Muras, A Parga, M Romero… - Frontiers in …, 2020 - frontiersin.org
… nosocomial pathogen Acinetobacter baumannii presents a quorum sensing (QS) system (abaI/abaR)
mediated by acyl-homoserine-lactones (AHLs) and several quorum quenching (QQ…

Attenuation of Quorum Sensing in the Pathogen Acinetobacter baumannii Using Non-native N-Acyl Homoserine Lactones

DM Stacy, MA Welsh, PN Rather… - ACS chemical …, 2012 - ACS Publications
… the activity of non-native AHLs in Acinetobacter baumannii, which has recently emerged as
a … baumannii was classified as a relatively low-grade, opportunist pathogen up until 30 years …