Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart: evidence for involvement of p38 MAPK
… To test whether the phosphorylation of p38 MAPK could be the site of the blockade of
genistein, we activated p38 MAPK with anisomycin and tested whether genistein could block the …
genistein, we activated p38 MAPK with anisomycin and tested whether genistein could block the …
Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart
C Weinbrenner, GS Liu, MV Cohen… - Journal of molecular and …, 1997 - Elsevier
… We investigated whether ischemic preconditioning also causes phosphorylation of the
activation sites on p38 MAPK. Three groups of isolated rabbit hearts were studied. Control hearts …
activation sites on p38 MAPK. Three groups of isolated rabbit hearts were studied. Control hearts …
p38 MAPK activity is not increased early during sustained coronary artery occlusion in preconditioned versus control rabbit heart
A Gysembergh, BZ Simkhovich, RA Kloner… - Journal of Molecular and …, 2001 - Elsevier
… (PC) involves increased activity of p38 mitogen-activated protein kinase (MAPK) early during
… buffer-perfused rabbit heart model of regional ischemia, we quantified p38 MAPK activity (…
… buffer-perfused rabbit heart model of regional ischemia, we quantified p38 MAPK activity (…
The contribution of reactive oxygen species and p38 mitogen‐activated protein kinase to myofilament oxidation and progression of heart failure in rabbits
P Heusch, M Canton, S Aker… - British journal of …, 2010 - Wiley Online Library
… and p38 MAP kinase activation were related to contractile function in failing rabbit hearts. …
Therefore, the present study used a HF model of LV pacing in rabbits to address: (i) the time …
Therefore, the present study used a HF model of LV pacing in rabbits to address: (i) the time …
Stress kinase phosphorylation is increased in pacing-induced heart failure in rabbits
R Schulz, S Aker, S Belosjorow… - … Physiology-Heart …, 2003 - journals.physiology.org
… Because MAPK phosphorylation and p38 MAPK activity … , when all rabbits had clinical signs
of severe heart failure and a … stage of heart failure JNK and p38 MAPK phosphorylation and …
of severe heart failure and a … stage of heart failure JNK and p38 MAPK phosphorylation and …
Phosphorylation state of hsp27 and p38 MAPK during preconditioning and protein phosphatase inhibitor protection of rabbit cardiomyocytes
SC Armstrong, M Delacey, CE Ganote - Journal of molecular and cellular …, 1999 - Elsevier
… of p38 MAPK is increased in basal medium, Eagle (BME)) and modified Eagle’s
preconditioned ischemic rabbit hearts during the … A functional role of the p38 MAPK path- …
preconditioned ischemic rabbit hearts during the … A functional role of the p38 MAPK path- …
SB 203580, an inhibitor of p38 MAPK, abolishes infarct-limiting effect of ischemic preconditioning in isolated rabbit hearts
A Nakano, MV Cohen, S Critz, JM Downey - Basic Research in Cardiology, 2000 - Springer
… In summary, this test of SB 203580, a p38 MAPK inhibitor, in whole rabbit hearts reveals
that the drug blocks the antiinfarct effect of ischemic preconditioning. Because the block …
that the drug blocks the antiinfarct effect of ischemic preconditioning. Because the block …
p38 MAP kinase mediates inflammatory cytokine induction in cardiomyocytes and extracellular matrix remodeling in heart
M Li, D Georgakopoulos, G Lu, L Hester, DA Kass… - Circulation, 2005 - Am Heart Assoc
… Horseradish peroxidase–conjugated goat anti-rabbit IgG was … Kinase assay for p38 was
performed with a p38 MAP kinase … transgenic hearts showed that activation of p38 MAP kinase …
performed with a p38 MAP kinase … transgenic hearts showed that activation of p38 MAP kinase …
Adenosine A1 Receptor Induced Delayed Preconditioning in Rabbits: Induction of p38 Mitogen-Activated Protein Kinase Activation and Hsp27 Phosphorylation via a …
A Dana, M Skarli, J Papakrivopoulou… - Circulation …, 2000 - Am Heart Assoc
… In the second part of the present study, we investigated this hypothesis by measuring p38
MAPK activity and expression and phosphorylation of Hsp27 in rabbit myocardium 24 hours …
MAPK activity and expression and phosphorylation of Hsp27 in rabbit myocardium 24 hours …
Activation of protein kinases in chronically hypoxic infant human and rabbit hearts: role in cardioprotection
P Rafiee, Y Shi, X Kong, KA Pritchard Jr, JS Tweddell… - Circulation, 2002 - Am Heart Assoc
… Effect of chelerythrine, a PKC inhibitor, on PKCε and p38 MAPK in chronically hypoxic rabbit
heart. … Effect of curcumin on JUN kinase and p38 MAPK in normoxic rabbit heart. Isolated …
heart. … Effect of curcumin on JUN kinase and p38 MAPK in normoxic rabbit heart. Isolated …
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