Aggregation and Binding Substances Enhance Pathogenicity in Rabbit Models of Enterococcus faecalis Endocarditis

PM Schlievert, PJ Gahr, AP Assimacopoulos… - Infection and …, 1998 - Am Soc Microbiol
aggregation substance (AS) and enterococcal binding substance (EBS) in rabbit models
of … First, American Dutch belted rabbits were injected intraventricularly with 10 8 CFU and …

Aggregation and Binding Substances Enhance Pathogenicity in a Rabbit Model of Enterococcus faecalis Endocarditis

PM Schlievert, GM Dunny, JA Stoehr… - Streptococci and the …, 1997 - Springer
… We investigated the importance of Aggregation Substance (AS) and Binding Substance (BS)
in a rabbit model of Enterococcus .faecalis endocarditis. Aggregation substance (AS), a …

Antibodies to a Surface-Exposed, N-terminal Domain of Aggregation Substance Are Not Protective in the Rabbit Model of Enterococcus faecalis Infective Endocarditis

JK McCormick, H Hirt, CM Waters, TJ Tripp… - Infection and …, 2001 - Am Soc Microbiol
… In the rabbit model of experimental endocarditis, we used a highly purified, surface-exposed …
from the conjugative plasmid pCF10) to immunize rabbits, followed by challenge with Asc10-…

Enterococcus faecalis Endocarditis Severity in Rabbits Is Reduced by IgG Fabs Interfering with Aggregation Substance

PM Schlievert, ON Chuang-Smith, ML Peterson… - PloS one, 2010 - journals.plos.org
… of large bacterial cell aggregates through binding to enterococcal binding substance (EBS),
a … than AS − organisms in a rabbit endocarditis model. The cumulative results of analysis of …

Release of a platelet-aggregating substance (adenosine diphosphate) from rabbit blood platelets induced by saline “extract” of tendons

T Hovig - Thrombosis and Haemostasis, 1963 - thieme-connect.com
… 16, 17) saline "extract" of tendons initiates platelet aggregation in vitro, and this effect is due
to … " releases an aggregating substance from the platelets, and that this substance is identical …

Plasmid-associated hemolysin and aggregation substance production contribute to virulence in experimental enterococcal endocarditis

JW Chow, LA Thal, MB Perri, JA Vazquez… - Antimicrobial agents …, 1993 - Am Soc Microbiol
… A rabbit endocarditis model was utilized to evaluate the virulence conferred by the conjugative
plasmid pADi with the following strains: Enterococcus faecalis plasmid-free FA2-2 and …

Aggregation of rabbit blood platelets produced in vitro by saline “extract” of tendons

T Hovig - Thrombosis and Haemostasis, 1963 - thieme-connect.com
aggregating substance for most of the experiments. These authors assumed the aggregating
substance to … In the present work some characteristics of the aggregating substance and its …

Substance P activates leukocytes and platelets in rabbit microvessels

A Öhlén, Å Thureson-Klein, L Lindbom… - Journal of Vascular …, 1989 - karger.com
… Local application of substance P caused vasodilatation and formation of aggregates of
platelets and … Aggregate formation induced by substance P could not be prevented by autacoid …

The induction of a rheumatoid factor-like substance in rabbits

JL Abruzzo, CL Christians - The Journal of Experimental Medicine, 1961 - rupress.org
… nonaggregated rabbit gamma globulin (7S-RGG), prepared by precipitation of pooled rabbit
… sulfate or ~ saturated sodium sulfate and aggregated rabbit gamma globulin (ARGG) which …

The rabbit as an experimental model

TH Burkholder, G Linton, RF Hoyt Jr… - … rabbit, guinea pig, hamster …, 2012 - Elsevier
rabbits are still a classic and frequently used model, murine models have been developed to
replace rabbits. … WHHL rabbit models. Unlike human patients with homozygous FH, WHHL …