Comparison of a rabbit model of bacterial endocarditis and an in vitro infection model with simulated endocardial vegetations

E Hershberger, EA Coyle, GW Kaatz… - Antimicrobial agents …, 2000 - Am Soc Microbiol
… and final bacterial densities in the SEVs were similar to those found in the rabbit vegetations…
indicates the in vitro model to be comparable to the rabbit model of endocarditis for study of …

Rabbit model of bacterial endocarditis

A Lefort, B Fantin - Handbook of animal models of infection, 1999 - Elsevier
… Routes of administration and schedule The rabbit experimental model of endocarditis has …
human pharmacokinetics in rabbits has improved the clinical relevance of the rabbit model to …

Evaluation of antimicrobial agents in the rabbit model of endocarditis

MA Sande - Reviews of infectious diseases, 1981 - academic.oup.com
… The rabbit model of bacterial endocarditis appears to be an effective and convenient
method to study various aspects of the disease, including the evaluation of potentially useful …

A new model for infective endocarditis of the mitral valve in rabbits

K Imataka, Y Kitahara, S Naito, J Fujii - American Heart Journal, 1993 - Elsevier
model of infective endocarditis without inserting catheters into the heart, we injected a bacterial
suspension into rabbits in … Experimental bacterial endocarditis. I. Colonization of a sterile …

Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of infective endocarditis

PM Sullam, AS Bayer, WM Foss… - Infection and …, 1996 - Am Soc Microbiol
rabbit model, animals inoculated with PS12 were significantly less likely to develop
endocarditis … of virulence in the pathogenesis of endocarditis. Staphylococcus-platelet binding …

Experimental bacterial endocarditis: III. Production and progress of the disease in rabbits

DT Durack, PB Beeson… - British journal of …, 1973 - ncbi.nlm.nih.gov
model for endocarditis in rabbits has been studied and standardized. Non-bacterial thrombotic
endocarditis … One day later, this was converted into bacterial endocarditis by single intra…

Efficacy of linezolid in a staphylococcal endocarditis rabbit model

MP Oramas-Shirey, LV Buchanan… - Journal of …, 2001 - academic.oup.com
… A rabbit model of aortic valve endocarditis developed by Garrison & Freedman 4 continues
to … Bacterial endocarditis is a lethal infection that requires the administration of high levels of …

Aggregation and Binding Substances Enhance Pathogenicity in Rabbit Models of Enterococcus faecalis Endocarditis

PM Schlievert, PJ Gahr, AP Assimacopoulos… - Infection and …, 1998 - Am Soc Microbiol
… This model has previously been used by other investigators to study bacterial endocarditis
(4, 9) and to demonstrate the importance of AS in virulence (9). For example, in a study by …

Rat model of experimental endocarditis

J Santoro, ME Levison - Infection and Immunity, 1978 - Am Soc Microbiol
… DISCUSSION The rabbit model of bacterial endocarditis has been useful in … -sided endocarditis
on the aortic valve of rabbits using viridans streptococci have produced similar bacterial

Influence of Staphylococcus aureus antibody on experimental endocarditis in rabbits

DP Greenberg, JI Ward, AS Bayer - Infection and immunity, 1987 - Am Soc Microbiol
… Prevention of staphylococcal IE has been studied in rabbits with Staphylococcus … aureus
endocarditis in rabbits. In the experimental endocarditis model, we evaluated the influence of …