… therapy, with increased metalloproteinase (MMP2) expression [84] and overall alteration
of … radiation fibrosis in humans is associated with increased collagen synthesis, altered …

… suppression of cutaneous radiation syndrome by … alterations are long term, and as such
they likely play a significant role in the development of the chronic fibrotic response to radiation …

… radiation-induced fibrosis risk, the knowledge of mechanisms and potential prevention has
become a crucial point to determining radiation … described the immune alteration in peripheral …

… risk minimization and early management of this condition when it was identified reduced the
development of secondary lymphedema after axillary dissection and altered its progression …

… In addition, the BET bromodomain proteins BRD2 and BRD4 are known readers of histone
acetylation at induced gene promoter sites and their expression is altered in radiation fibrosis-…

… This cellular response to radiation would result in an altered diå erentiation pattern of the
modulation of ®broblast proliferation and diå erentiation. Using a co-culture system of …

… on tissue fibrosis, which is a major late radiation damage. … early alterations of TGF-β
expression could allow a better understanding of the immediate cell response to ionizing radiation. …

… that alterations in expression of extracellular matrix and TGFβ mRNA occur very early after
radiation injury even at low doses and may play a role in the development of chronic fibrosis. …

… of the surrounding normal tissues to prevent toxicities such as fibrosis. … alterations leading
to fibrosis. Although it is known that fibrosis is caused by excess collagen and alterations in …

… Only mmp12, il6, and il13 genes were altered in both irradiated left lungs and non-irradiated …
alteration was observed in both 90Gy and 20Gy irradiated lungs, except for slight alterations …