Radiation produces differential changes in cytokine profiles in radiation lung fibrosis sensitive and resistant mice

X Ao, L Zhao, MA Davis, DM Lubman… - Journal of hematology & …, 2009 - Springer
… C3H mouse strains in their response to lung radiation [11–14]. C57BL/6 mice are much more
sensitive to radiation-induced pulmonary fibrosis than C3H mice [15]. Johnston et al. have …

Computed tomography monitoring of radiation-induced lung fibrosis in mice

C Plathow, M Li, P Gong, H Zieher… - Investigative …, 2004 - journals.lww.com
… density changes of the lung parenchyma in mice after RT using thin-section CT and
characteristic parameters of human lung fibrosis. The onset of developing lung fibrosis in CT was …

Molecular mechanisms and treatment of radiation-induced lung fibrosis

NH Ding, J Jian Li, LQ Sun - Current drug targets, 2013 - ingentaconnect.com
… inflammatory response to radiation-induced lung injury and degrade collagen IV in the
basement membrane [78]. MMP13-deficient mice developed less pulmonary fibrosis than their …

Radiation-induced lung fibrosis: preclinical animal models and therapeutic strategies

H Jin, Y Yoo, Y Kim, Y Kim, J Cho, YS Lee - Cancers, 2020 - mdpi.com
radiation pneumonitis and chronic radiation-induced lung fibrosis, is the most common side
effect of radiation … Gy to the entire left lung of C57BL/6 mice, and a significant amount of lung

The inflammasome accelerates radiation-induced lung inflammation and fibrosis in mice

SH Sohn, JM Lee, S Park, H Yoo, JW Kang… - Environmental …, 2015 - Elsevier
… Additional pathway of radiation-induced pneumonitis and fibrosis To evaluate potential
pathways that may be activated during of radiation-induced pneumonitis and fibrosis in the lung, …

Fibroblast radiosensitivity in vitro and lung fibrosis in vivo: comparison between a fibrosis-prone and fibrosis-resistant mouse strain

CL Dileto, EL Travis - Radiation research, 1996 - meridian.allenpress.com
… differences in radiation-induced lung fibrosis observed in the … that radiation induces two
types of fibrosis in the mouse colon, … fibrotic lesion in the irradiated lungs of the C57BL/6J mice

Identification of molecular signatures involved in radiation-induced lung fibrosis

H Jin, GY Kang, S Jeon, JM Kim, YN Park… - Journal of Molecular …, 2019 - Springer
lung damage [7]. In this study, to identify molecular signatures for IR-induced lung fibrosis,
we further examined the fibrosis … as irradiated region from mouse lung tissues after HDFR (90 …

Role of type II pneumocyte senescence in radiation-induced lung fibrosis

DE Citrin, U Shankavaram, JA Horton… - Journal of the …, 2013 - academic.oup.com
… To confirm the importance of NOX in radiation fibrosis, mice were treated with DPI (1mg/kg/…
Treatment with DPI markedly reduced pulmonary fibrosis after radiation at 16 weeks …

Dose-dependent induction of transforming growth factor β (TGF-β) in the lung tissue of fibrosis-prone mice after thoracic irradiation

CE Rübe, D Uthe, KW Schmid, KD Richter… - … Journal of Radiation …, 2000 - Elsevier
… and progression of fibrotic tissue reactions. … radiation on the gene expression of transforming
growth factor beta (TGF-β) in a model of lung injury using fibrosis-sensitive C57BL/6 mice

Radiation-induced lung fibrosis in a tumor-bearing mouse model is associated with enhanced Type-2 immunity

J Chen, Y Wang, Z Mei, S Zhang, J Yang… - Journal of radiation …, 2016 - academic.oup.com
lung tissue aggravates lung fibrosis in a tumor model, we subjected mice with lung cancer
to X-ray irradiation and assessed Type-2 immunity and the degree of lung fibrosis. In addition, …