Radiation response modification following molecular inhibition of epidermal growth factor receptor signaling
PM Harari, SM Huang - Seminars in radiation oncology, 2001 - Elsevier
… with ionizing radiation and anti-epidermal growth factor receptor monoclonal antibody
C225 … L, et ah Physical interaction between epidermal growth factor receptor and DNA-dependent …
C225 … L, et ah Physical interaction between epidermal growth factor receptor and DNA-dependent …
Epidermal growth factor family receptors and inhibitors: radiation response modulators
CI Sartor - Seminars in radiation oncology, 2003 - Elsevier
… Growing evidence suggests that epidermal growth factor family receptors (HERs) play a
significant role in radiation response. … The epidermal growth factor receptor family consists of 4 …
significant role in radiation response. … The epidermal growth factor receptor family consists of 4 …
Epidermal growth factor receptor and tumor response to radiation: in vivo preclinical studies
L Milas, Z Fan, NH Andratschke, KK Ang - … Journal of Radiation Oncology …, 2004 - Elsevier
… Evidence is rapidly mounting that dysregulated epidermal growth factor receptor (EGFR) …
and increased tumor resistance to cytotoxic agents, including radiotherapy (RT). This has led to …
and increased tumor resistance to cytotoxic agents, including radiotherapy (RT). This has led to …
Targeting the epidermal growth factor receptor in radiotherapy: radiobiological mechanisms, preclinical and clinical results
M Baumann, M Krause - Radiotherapy and oncology, 2004 - Elsevier
… Inhibition of the epidermal growth factor receptor (EGFR) is a fastly developing field in …
mechanisms which may underly the efficacy of EGFR inhibitors combined with irradiation. …
mechanisms which may underly the efficacy of EGFR inhibitors combined with irradiation. …
The epidermal growth factor receptor mediates radioresistance
K Liang, KK Ang, L Milas, N Hunter, Z Fan - … Journal of Radiation Oncology …, 2003 - Elsevier
… EGF receptors. We then examined cellular response to radiation of clonal cells that were
selected for high-expression levels of EGF receptors. We found that overexpression of EGF …
selected for high-expression levels of EGF receptors. We found that overexpression of EGF …
Angiogenesis and radiation response modulation after vascular endothelial growth factor receptor-2 (VEGFR2) blockade
J Li, S Huang, EA Armstrong, JF Fowler… - … Journal of Radiation …, 2005 - Elsevier
… Combination of vascular endothelial growth factor receptor 2 blockade and radiation.
Athymic mice bearing (a) squamous cell carcinoma-1 or (b) squamous cell carcinoma-6 tumors …
Athymic mice bearing (a) squamous cell carcinoma-1 or (b) squamous cell carcinoma-6 tumors …
Epidermal growth factor receptor signaling and response of cancer cells to ionizing radiation
SP Ethier, TS Lawrence - Journal of the National Cancer …, 2001 - academic.oup.com
… against growth factor receptors with radiation offers an exciting potential advance in cancer
treatment. To take full advantage of this potential, it will be crucial to design clinical trials …
treatment. To take full advantage of this potential, it will be crucial to design clinical trials …
Personalized radiation oncology: epidermal growth factor receptor and other receptor tyrosine kinase inhibitors
GS Higgins, M Krause, WG McKenna… - Molecular Radio …, 2016 - Springer
… The receptor tyrosine kinases (RTK) are described in the following text. Among them, the …
growth factor receptor (EGFR) that plays a major role for prognosis of patients after radiotherapy…
growth factor receptor (EGFR) that plays a major role for prognosis of patients after radiotherapy…
Enhancement of antitumor activity of ionizing radiation by combined treatment with the selective epidermal growth factor receptor-tyrosine kinase inhibitor ZD1839 …
C Bianco, G Tortora, R Bianco, R Caputo… - Clinical cancer …, 2002 - AACR
… Purpose: The epidermal growth factor receptor (EGFR) is expressed in the majority of …
Radiation response modification following molecular inhibition of epidermal growth factor receptor …
Radiation response modification following molecular inhibition of epidermal growth factor receptor …
[HTML][HTML] Molecular targeting in radiotherapy: epidermal growth factor receptor
TD Chung, WC Broaddus - Molecular Interventions, 2005 - triggered.clockss.org
… aspects of radiation biology have revealed that the radiation response is mediated through
… will selectively enhance the radiation killing of tumor cells. Ionizing radiation (IR) induces …
… will selectively enhance the radiation killing of tumor cells. Ionizing radiation (IR) induces …
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