Efficacy and safety of tarenflurbil in mild to moderate Alzheimer's disease: a randomised phase II trial

GK Wilcock, SE Black, SB Hendrix, KH Zavitz… - The Lancet …, 2008 - thelancet.com
… In summary, this phase II study provides preliminary evidence of a possible therapeutic effect
of tarenflurbil, the first SALA to complete a phase II evaluation. In patients with mild AD, 800 …

[HTML][HTML] Gemcitabine-based or capecitabine-based chemoradiotherapy for locally advanced pancreatic cancer (SCALOP): a multicentre, randomised, phase 2 trial

S Mukherjee, CN Hurt, J Bridgewater, S Falk… - The lancet …, 2013 - thelancet.com
… In this open-label, randomised, two-arm, phase 2 trial, patients aged 18 years or older with
histologically proven, locally advanced pancreatic cancer (with a tumour diameter of 7 cm or …

Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial

C Becker, SR Lord, SA Studenski… - The lancet Diabetes & …, 2015 - thelancet.com
… In this proof-of-concept, randomised, placebo-controlled, double-blind, parallel, multicentre,
phase 2 study, we recruited patients aged 75 years or older who had fallen in the past year …

Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial

AM Oza, D Cibula, AO Benzaquen, C Poole… - The lancet …, 2015 - thelancet.com
… To our knowledge, our phase 2 trial is the first to show that, compared with chemotherapy
alone, patients with relapsed ovarian cancer respond preferentially to a PARP inhibitor in …

Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial

G Folprecht, T Gruenberger, WO Bechstein… - The lancet …, 2010 - thelancet.com
… This was an open, multicentre randomised phase 2 study that examined the effectiveness
of … of unresectable colorectal liver metastases (CELIM trial). The primary endpoint was …

A randomised phase 2 trial of dexamethasone versus prednisolone in castration-resistant prostate cancer

R Venkitaraman, D Lorente, V Murthy, K Thomas… - European urology, 2015 - Elsevier
… We conducted a randomised phase 2 trial comparing dexamethasone and prednisolone to
explore this hypothesis. We initially tested two different dose schedules for dexamethasone, …

Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: an open label, randomised, phase 2 trial

R Aft, M Naughton, K Trinkaus, M Watson… - The lancet …, 2010 - thelancet.com
… We did a randomised phase 2 study to investigate the effects of zoledronic acid on DTCs,
bone-… density, in women undergoing neoadjuvant chemotherapy for stage II–III breast cancer. …

Olaratumab and doxorubicin versus doxorubicin alone for treatment of soft-tissue sarcoma: an open-label phase 1b and randomised phase 2 trial

WD Tap, RL Jones, BA Van Tine, B Chmielowski… - The Lancet, 2016 - thelancet.com
… We searched PubMed for all randomised trials in English that involved single-drug …
randomized”, and “trial”. We identified 19 randomised phase 2 or phase 3 clinical trials, none of …

Is concurrent radiation therapy required in patients receiving preoperative chemotherapy for adenocarcinoma of the oesophagus? A randomised phase II trial

BH Burmeister, JM Thomas, EA Burmeister… - European journal of …, 2011 - Elsevier
… We report the outcomes of a randomised phase II trial comparing preoperative CT and
CRT for resectable adenocarcinoma of the oesophagus and gastro-oesophageal junction. …

Bone-targeted therapy for advanced androgen-independent carcinoma of the prostate: a randomised phase II trial

SM Tu, RE Millikan, B Mengistu, ES Delpassand… - The Lancet, 2001 - thelancet.com
… to indicate the best option in a randomised phase II trial.16 This number of patients would …
eligible patients who would also participate in randomisation to a consolidation therapy. This …