… erlotinib plus bevacizumab vs erlotinib alone on progression-free survival in patients with advanced EGFR-mutant non–small cell lung cancer: a phase 2 randomized …

TE Stinchcombe, PA Jänne, X Wang, EM Bertino… - JAMA …, 2019 - jamanetwork.com
… The Cancer and Leukemia Group B trial 30406 was a randomized phase 2 clinical trial
that investigated erlotinib alone or with carboplatin and paclitaxel in patients with a history of …

Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer

EB Garon, JM Siegfried, LP Stabile, PA Young… - Lung Cancer, 2018 - Elsevier
… , randomized phase II trial examined the efficacy and safety of combination erlotinib plus
fulvestrant compared to erlotinib alone for … in PFS or OS with erlotinib plus fulvestrant among all …

Sunitinib plus erlotinib versus placebo plus erlotinib in patients with previously treated advanced non–small-cell lung cancer: a phase III trial

GV Scagliotti, M Krzakowski, A Szczesna… - Journal of clinical …, 2012 - ascopubs.org
… NSCLC, sunitinib plus erlotinib did not improve OS compared with erlotinib alone, but the …
In summary, in this global, randomized, phase III trial in patients with NSCLC previously …

Randomized, double-blind, placebo-controlled, phase II trial of sorafenib and erlotinib or erlotinib alone in previously treated advanced non–small-cell lung cancer

DR Spigel, HA Burris III, FA Greco… - Journal of clinical …, 2011 - ascopubs.org
phase III trial, bevacizumab was added to erlotinib in patients with relapsed NSCLC. Although
PFS was improved with the combination compared with erlotinib alonerandomized phase

Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non–small-cell lung cancer

TSK Mok, YL Wu, CJ Yu, C Zhou, YM Chen… - Journal of Clinical …, 2009 - ascopubs.org
… in four randomized phase III trials. In these studies, concurrent administration of erlotinib or
… not improve survival compared with chemotherapy alone. Preclinical evidence suggests that …

[HTML][HTML] Randomized, phase III trial of figitumumab in combination with erlotinib versus erlotinib alone in patients with nonadenocarcinoma nonsmall-cell lung cancer

GV Scagliotti, I Bondarenko, F Blackhall, F Barlesi… - Annals of …, 2015 - Elsevier
… This multicenter, randomized, phase III study investigated the efficacy of figitumumab plus
erlotinib compared with erlotinib alone in patients with pretreated, nonsmall-cell lung cancer (…

A randomized phase III study of combining erlotinib with bevacizumab and panitumumab versus erlotinib alone as second-line therapy for Chinese patients with non …

Y Wang, H Wang, Y Jiang, Y Zhang, X Wang - Biomedicine & …, 2017 - Elsevier
… study is that patients treated with erlotinib with bevacizumab and panitumumab had much
severe adverse events than those treated with erlotinib alone. Future study may be needed to …

Erlotinib plus bevacizumab versus erlotinib alone in patients with EGFR-positive advanced non-squamous non-small-cell lung cancer (NEJ026): interim analysis of an …

H Saito, T Fukuhara, N Furuya, K Watanabe… - The Lancet …, 2019 - thelancet.com
… first phase 3 study to compare the efficacy of erlotinib plus bevacizumab with erlotinib alone
… The results from this interim analysis suggest that patients given bevacizumab and erlotinib

Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma …

PA Jänne, X Wang, MA Socinski, J Crawford… - Journal of clinical …, 2012 - ascopubs.org
… been solely the result of increased efficacy of erlotinib in never smokers and/or in patients …
We thus developed a randomized phase II trial to investigate the efficacy of erlotinib alone and …

Phase I/II trial of cetuximab and erlotinib in patients with lung adenocarcinoma and acquired resistance to erlotinib

YY Janjigian, CG Azzoli, LM Krug, LK Pereira… - Clinical cancer …, 2011 - AACR
erlotinib is less toxic (8). Gefitinib showed a progression-free survival (PFS) advantage over
chemotherapy as a first-line therapy in 3 randomized phase III … neither agent alone, induced …