… This randomized phase III trial was designed to compare … for each agent, this phase III study
has demonstrated that docetaxel … study are consistent with those reported for previous phase …

… Based on the composite experience from these recent phase III studies, we suggest
strategies to aid future development and testing that may help bring this potentially powerful and …

Purpose The National Surgical Adjuvant Breast and Bowel Project C-08 trial was designed
to investigate the safety and effectiveness of adding bevacizumab to modified infusional …

… Study Design and Treatment The study was an open-label, randomized phase III study in …
The study was designed to compare the efficacy, safety, and tolerability of elacytarabine as a …

… We conducted a randomized phase III study investigating the efficacy of S-1 as adjuvant
chemotherapy for colon cancer by evaluating its noninferiority to tegafur–uracil plus leucovorin (…

… to single-agent DTIC chemotherapy in phase III clinical studies. The combination of chemotherapy
… , although a number of promising regimens are now being tested in phase III studies. …

… studies showed downstaging with pCR of more than 15% after preoperative CRT compared
with approximately 5% after RT alone. This randomized phase III study … this randomized trial …

… A pivotal phase III study 1 demonstrated that the addition of … We had initially begun a
randomized phase III trial, designated … After the pivotal phase III data for bevacizumab became …

… This randomized phase III study evaluated the efficacy and safety of the novel topoisomerase
… not met and thus this randomized phase III trial should be regarded as a negative study. …

Purpose This phase III international study compared the efficacy and safety of a combination
of pegylated liposomal doxorubicin (PLD) plus bortezomib with bortezomib monotherapy in …