Efficacy of concurrent chemoradiotherapy with S-1 vs radiotherapy alone for older patients with esophageal cancer: a multicenter randomized phase 3 clinical trial
Y Ji, X Du, W Zhu, Y Yang, J Ma, L Zhang, J Li… - JAMA …, 2021 - jamanetwork.com
… To our knowledge, this is the first randomized phase 3 trial that aimed to assess the
efficacy of an optimized CCRT regimen for older patients with esophageal cancer. Our results …
efficacy of an optimized CCRT regimen for older patients with esophageal cancer. Our results …
… of gemtuzumab ozogamicin and standard chemotherapy in older patients with newly diagnosed acute myeloid leukemia: results of a randomized phase III trial by the …
S Amadori, S Suciu, R Stasi, HR Salih… - Journal of clinical …, 2013 - ascopubs.org
Purpose This randomized trial evaluated the efficacy and toxicity of sequential gemtuzumab
ozogamicin (GO) and standard chemotherapy in older patients with newly diagnosed acute …
ozogamicin (GO) and standard chemotherapy in older patients with newly diagnosed acute …
Enasidenib vs conventional care in older patients with late-stage mutant-IDH2 relapsed/refractory AML: a randomized phase 3 trial
S de Botton, P Montesinos, AC Schuh, C Papayannidis… - Blood, 2023 - ashpublications.org
… -arm trial, we conducted a randomized phase 3 trial to evaluate the efficacy and safety of
enasidenib vs conventional care regimens (CCRs) in older patients with late-stage, heavily …
enasidenib vs conventional care regimens (CCRs) in older patients with late-stage, heavily …
… versus best supportive care in older patients with newly diagnosed acute myeloid leukemia unsuitable for intensive chemotherapy: results of the randomized phase III …
S Amadori, S Suciu, D Selleslag, F Aversa… - Journal of Clinical …, 2016 - ascopubs.org
… the treatment of relapsed AML in older patients ineligible for intensive chemotherapy. This …
30% observed in phase II trials. However, results in older patients with newly diagnosed AML …
30% observed in phase II trials. However, results in older patients with newly diagnosed AML …
[HTML][HTML] … from PRODIGE 20 randomized phase II trial evaluating bevacizumab+ chemotherapy versus chemotherapy alone in older patients with untreated metastatic …
T Aparicio, O Bouché, E Francois, F Retornaz… - European Journal of …, 2018 - Elsevier
… choices for older patients. The PRODIGE 20 study is a randomized phase II study that
evaluated … associated with bevacizumab (BEV) or not (CT) in patients aged 75 years or older. …
evaluated … associated with bevacizumab (BEV) or not (CT) in patients aged 75 years or older. …
A randomized phase II trial of geriatric assessment and management for older cancer patients
MTE Puts, S Sattar, M Kulik, ME MacDonald… - Supportive care in …, 2018 - Springer
… phase 3 randomized controlled trial (RCT) of GA + ICP, we conducted a randomized phase
… older patients with advanced breast (BC), gastrointestinal (GI), or genitourinary (GU) cancers. …
… older patients with advanced breast (BC), gastrointestinal (GI), or genitourinary (GU) cancers. …
Results from a randomized phase III trial of decitabine versus supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed AML.
XG Thomas, A Dmoszynska, A Wierzbowska… - Journal of Clinical …, 2011 - ascopubs.org
… Conclusions: Compared with the accepted standard therapies used in this study to treat
older patients with AML, DAC showed an overall survival advantage and higher response rates …
older patients with AML, DAC showed an overall survival advantage and higher response rates …
[HTML][HTML] Subgroup analysis of older patients treated within the randomized phase 3 doxorubicin versus doxorubicin plus evofosfamide (SARC021) trial
… In this study, older patients were defined as those aged 65 years or older. A retrospective …
performed to identify older patients and those aged <65 years. Patient demographics, clinical …
performed to identify older patients and those aged <65 years. Patient demographics, clinical …
[HTML][HTML] Randomized phase III trial in elderly patients comparing LV5FU2 with or without irinotecan for first-line treatment of metastatic colorectal cancer (FFCD 2001 …
T Aparicio, S Lavau-Denes, JM Phelip, E Maillard… - Annals of …, 2016 - Elsevier
… alone, showed that irinotecan improved PFS in patients over 70 years but not in patients
over 75 years. The lack of difference in the older patients may have been due to their small …
over 75 years. The lack of difference in the older patients may have been due to their small …
Efficacy of a comprehensive geriatric intervention in older patients hospitalized for hip fracture: a randomized, controlled trial
M Vidán, JA Serra, C Moreno… - Journal of the …, 2005 - Wiley Online Library
… In this randomized trial, it was not possible to demonstrate a significant reduction in length
… during hospitalization in the orthopedic ward in older patients with a hip fracture. On the …
… during hospitalization in the orthopedic ward in older patients with a hip fracture. On the …
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