… EGFR mutations responsible for primary or acquired resistance against TKI therapy. , 5 In
addition, many rare EGFR mutations (… 18–21] of EGFR excluding exon 19 microdeletions and …

… that the absolute number of rare EGFR mutations in certain patient … Moreover, the term rare
EGFR mutation describes a very … and epidemiology of all EGFR mutations for different patient …

… In line with these data, it is rare to see small cell or squamous cell carcinomas in never-…
EGFR mutation incidence or smoking habit in conduction with sex, are markedly different …

… The small sample sizes available also contributed to a major limitation of this analysis: each
study included different uncommon mutations, or grouped these mutations differently, and …

… This study reviewed the prevalence of uncommon EGFR mutations and their sensitivity to …
Two different methods, with different limits of detection (LOD), were used in this study. Among …

… Sample numbers for these rare mutations were too low for … literature 5 demonstrated an
EGFR mutation prevalence of 45% … carcinomas arising in smokers is distinct from that in tumors …

… of EGFR-TKIs in patients carrying uncommon EGFR mutations. The incidence of rare
mutations varies in different … In conclusion, distinct clinical features of different EGFR co-mutations …

… However, the sensitivity of uncommon EGFR mutations to the different classes of EGFR
TKIs may significantly vary, since some have increased sensitivity to second-generation …

… rare and/or complex mutations. In our study, 12% of lung adenocarcinomas carried an EGFR
mutation, a prevalence … predictive role of different uncommon mutations by dividing patients …

… rare pathological subtype with poor prognosis, with no confirmed evidence about its
epidemiological features or therapeutic efficiency of EGFR… on the left side was distinctly …