Cytokines regulate matrix metalloproteinases and migration in cardiac fibroblasts

RD Brown, GM Jones, RE Laird, P Hudson… - … and biophysical research …, 2007 - Elsevier
… In the present study, we addressed these issues using cultured cardiac fibroblasts from adult
rats. In addition we examined the role of MAP kinase activation in cytokine stimulated MMP …

Angiotensin II enhances integrin and α-actinin expression in adult rat cardiac fibroblasts

H Kawano, RJ Cody, K Graf, S Goetze, Y Kawano… - …, 2000 - Am Heart Assoc
… and extracellular matrix (ECM) production in cardiac fibroblasts. Integrins are a family of … to
its role in cardiac remodeling. We cultured adult rat cardiac fibroblasts with and without Ang II (…

Tumor Necrosis Factor-α at Acute Myocardial Infarction in Rats andÈEffects on Cardiac Fibroblasts

M Jacobs, S Staufenberger, U Gergs, K Meuter… - Journal of molecular and …, 1999 - Elsevier
… Now, in a rat model of acute myocardial infarction TNF- expression and effects on cardiac
fibroblast were determined. TNF- was detected in rat hearts with acute myocardial infarction, …

Involvement of reactive oxygen species in angiotensin II-induced endothelin-1 gene expression in rat cardiac fibroblasts

TH Cheng, PY Cheng, NL Shih, IB Chen… - Journal of the American …, 2003 - jacc.org
… Cultured neonatal rat cardiac fibroblasts were stimulated with Ang II, and then [ 3 H]thymidine
incorporation and the ET-1 gene expression were examined. We also examined the effects …

CTGF expression is induced by TGF-β in cardiac fibroblasts and cardiac myocytes: a potential role in heart fibrosis

MM Chen, A Lam, JA Abraham, GF Schreiner… - Journal of molecular and …, 2000 - Elsevier
cardiac injury is not fully understood. Here, we show that TGF- is a specific inducer of CTGF
expression in both cardiac fibroblasts and cardiac … ) and neonatal rat cardiac fibroblasts were …

[HTML][HTML] Angiotensin II induced differentially expressed microRNAs in adult rat cardiac fibroblasts

X Jiang, Q Ning, J Wang - The journal of physiological sciences, 2013 - Springer
Cardiac fibroblasts (CFs) are the most numerous cell type in the heart, accounting for …
CON-123 indicates control cardiac fibroblasts. DRUG-123 indicates cardiac fibroblasts treated by …

Cardiac fibroblasts: friend or foe?

TA Baudino, W Carver, W Giles… - American Journal of …, 2006 - journals.physiology.org
… the cardiac fibroblast. Under appropriate stimulation, relatively quiescent fibroblasts can …
(118) have studied the electrophysiology of cultured neonatal rat cardiac fibroblasts. These …

Cardiac fibroblasts: function, regulation of gene expression, and phenotypic modulation

M Eghbali - Cardiac Adaptation in Heart Failure: Risks due to …, 1992 - Springer
… and factors on cardiac fibroblasts behavior, we have established cultured cardiac fibroblasts
from rat and … In both preparations cardiac fibroblasts showed many characteristics shared by …

TGFβ, cardiac fibroblasts, and the fibrotic response

A Leask - Cardiovascular research, 2007 - academic.oup.com
… In a rat model of cardiac fibrosis, the ERK pathway, in addition to the Smads, is activated
and may contribute to Ang II-induced fibrosis in this model [25]. Thus understanding how TGFβ …

Cardiac fibroblast to myofibroblast differentiation in vivo and in vitro: expression of focal adhesion components in neonatal and adult rat ventricular myofibroblasts

JJ Santiago, AL Dangerfield, SG Rattan… - Developmental …, 2010 - Wiley Online Library
… Contractile, focal adhesion-associated, receptor proteins, fibroblast growth factor-2 (FGF-2) …
neonatal rat cardiac fibroblasts and myofibroblasts. Neonatal and adult fibroblasts undergo …