Characterization of the peripheral action of neurokinins and neurokinin receptor selective agonists on the rat cardiovascular system

R Couture, O Laneuville, C Guimond… - Naunyn-Schmiedeberg's …, 1989 - Springer
… substance P (SP), neurokinin A (NKA), neurokinin B (NKB) and selective agonists for neurokinin
receptors were measured after intravenous (iv) injection in urethane anaesthetized rats. …

Substance P acting via the neurokinin-1 receptor regulates adverse myocardial remodeling in a rat model of hypertension

HM Dehlin, EJ Manteufel, AL Monroe… - International journal of …, 2013 - Elsevier
… a series of experiments using adult rat isolated cardiac fibroblasts. Firstly, we determined
that cardiac fibroblasts possessed the NK-1 receptor using western blotting (Supplemental Fig. …

Tachykinins and the cardiovascular system

DA Walsh, DF McWilliams - Current drug targets, 2006 - ingentaconnect.com
… by the NK2 receptor antagonist SR48968 in chronically hypoxic rat lungs [185]. There may,
however, be marked interspecies variations in the distributions of neurokinin receptors, and …

Role of substance P in the cardiovascular system

E Mistrova, P Kruzliak, MC Dvorakova - Neuropeptides, 2016 - Elsevier
… with the highest affinity to neurokinin receptor 1. Substance P … nervous systems as well as
in the cardiovascular system. … receptor was detected in the right atrium of STZ-treated rats. …

Characterization of the peripheral action of neuropeptide K on the rat cardiovascular system

A Décarie, R Couture - European journal of pharmacology, 1992 - Elsevier
receptors (Takcda and Krause, 19891. The present study was undertaken to examine the
effect of NPK on the rat cardiovascular system… of neurokinins and neurokinin receptor selective …

Chronic activation of neurokinin-1 receptor induces pulmonary hypertension in rats

LW Chen, CF Chen, YL Lai - … -Heart and Circulatory …, 1999 - journals.physiology.org
… chronic activation of neurokinin-1 (NK-1) receptor induces pulmonary hypertension in Wistar
rats. First, the activation of NK-1 receptor on the pulmonary circulation was investigated by …

Substance P and neurokinin A induced desentization to cardiovascular and behavioral effects: evidence for the involvement of different tachykinin receptors

J Culman, C Tschöpe, N Jost, K Itoi, T Unger - Brain research, 1993 - Elsevier
receptors but neither NK 2 binding sites nor the mRNA encoding for the NK 2 receptor have
been convincingly identified in the adult rat … involvement of NK 1 receptors in mediating the …

Cardiovascular and behavioural effects of centrally administered tachykinins in the rat: characterization of receptors with selective antagonists

P Picard, D Regoli, R Couture - British journal of pharmacology, 1994 - Wiley Online Library
… Table 3 Effects of selective tachykinin receptor antagonists on behavioural responses
elicited by the substance P (SP), neurokinin A (NKA) or [MePhe']NKB in the conscious rat icv …

Kinin B1 receptors and the cardiovascular system: regulation of expression and function

PG McLean, M Perretti, A Ahluwalia - Cardiovascular research, 2000 - academic.oup.com
… inhibited by B 1 receptor blockade and by neurokinin and CGRP receptor antagonists [113]. …
In this study administration of LPS to rats resulted in an increase in circulating bradykinin …

[HTML][HTML] Involvement of neurokinin-1 receptors in the autonomic nervous system in colorectal distension-induced cardiovascular suppression in rats

K Kurogochi, M Uechi, K Orito - Frontiers in Pharmacology, 2022 - frontiersin.org
neurokinin-1 receptor might be involved in the autonomic nervous system, and that a neurokinin-1
receptor … This study used a rat model in which the reflex was induced by afferent vagal …