Global cardiac remodeling after acute myocardial infarction: a study in the rat model

HF Weisman, DE Bush, JA Mannisi… - Journal of the American …, 1985 - Elsevier
… of infarction in the rat heart progresses at about twice the rate that it does in the human heart.
It is … faster in the rat than in the human subject. However, even if this were true, early remote …

Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure

S Kim, M Yoshiyama, Y Izumi, H Kawano, M Kimoto… - Circulation, 2001 - Am Heart Assoc
… in hypertensive rats 8 9 and normotensive volunteers 10 and improve cardiac function or
hemodynamic status in pacing-induced pig heart failure 11 and postischemic rat heart failure …

Cardiac remodeling by fibrous tissue after infarction in rats

Y Sun, JQ Zhang, J Zhang, S Lamparter - Journal of Laboratory and Clinical …, 2000 - Elsevier
… In the present study we sought to assess the time course of collagen remodeling in the
infarcted rat hearts by detecting spatial and time-dependent cellular events related to collagen …

Therapeutic effect of midkine on cardiac remodeling in infarcted rat hearts

S Fukui, S Kitagawa-Sakakida, S Kawamata… - The Annals of thoracic …, 2008 - Elsevier
… Our results indicate midkine can attenuate cardiac remodeling after myocardial infarction,
and suggest midkine has therapeutic potential for subacute myocardial infarction. …

Critical role of Rho-kinase pathway for cardiac performance and remodeling in failing rat hearts

N Kobayashi, S Horinaka, S Mita… - Cardiovascular …, 2002 - academic.oup.com
… that regulate cardiac function and cardiovascular remodeling, … -sensitive hypertensive rats
with congestive heart failure (CHF) … chain phosphorylations in CHF rats were suppressed by Y-…

Advanced glycation endproducts: activators of cardiac remodeling in primary fibroblasts from adult rat hearts

S Daoud, R Schinzel, A Neumann, C Loske… - Molecular …, 2001 - Springer
heart (11,12), our results support the hypothesis that prolonged elevated levels of AGEs
contribute to cardiac remodeling, which is an important step in the induction of cardiac fibrosis. …

Collagen remodeling after myocardial infarction in the rat heart.

JP Cleutjens, MJ Verluyten, JF Smiths… - The American journal …, 1995 - ncbi.nlm.nih.gov
… Paraffin sections (6 pm) of all four levels of each rat heart from the same series of rats as
used for in situ hybridization were stained for 90 minutes with Sirius red (Polysciences, …

Cardiac remodeling after long term norepinephrine treatment in rats

W Briest, A Hölzl, B Raßler, A Deten… - Cardiovascular …, 2001 - academic.oup.com
… -2 activity in rat hearts by stimulation of cardiac adrenergic receptors. These results indicate
the significance of MMPs for the regulation of remodeling of the ECM after NE treatment. …

Cardiac sympathetic afferent denervation attenuates cardiac remodeling and improves cardiovascular dysfunction in rats with heart failure

HJ Wang, W Wang, KG Cornish, GJ Rozanski… - …, 2014 - Am Heart Assoc
… Here, we determined the effects of chronic CSAR deletion on cardiac remodelingcardiac
sympathetic afferent deletion exhibits protective effects against deleterious cardiac remodeling

Severe myocardial dysfunction induced by ventricular remodeling in aging rat hearts

JM Capasso, T Palackal, G Olivetti… - … of Physiology-Heart …, 1990 - journals.physiology.org
… The results of the present study indicate that the aging process of the heart in Fischer 344
rats leads to alterations in global cardiac hemodynamics that were found in senescent animals …