San‐Huang‐XieXin‐tang prevents rat hearts from ischemia/reperfusion‐induced apoptosis through eNOS and MAPK pathways

SF Liou, HJ Ke, JH Hsu, JC Liang… - Evidence‐Based …, 2011 - Wiley Online Library
San‐Huang‐XieXin‐Tang (SHXT) is a traditional Chinese medication consisting of three
herbs, namely Coptidis rhizome, Scutellariae radix and Rhei rhizome. This study aimed to …

[HTML][HTML] Sevoflurane post-conditioning protects isolated rat hearts against ischemia-reperfusion injury via activation of the ERK1/2 pathway

H Xie, J Zhang, J Zhu, L Liu, M Rebecchi… - Acta Pharmacologica …, 2014 - nature.com
… In the present study, we chose 3% sevoflurane to post-condition the isolated rat hearts in
a Langendorff perfusion system 28 . Intracellular mitogen-activated protein kinases (MAPKs) …

[HTML][HTML] Berberine Mediated Positive Inotropic Effects on Rat Hearts via a Ca2+-Dependent Mechanism

J Zhao, Y Wang, J Gao, Y Jing, W Xin - Frontiers in Pharmacology, 2020 - frontiersin.org
… at 20 µM in Langendorff-perfused isolated rat hearts. These effects diminished with the …
In conclusion, berberine might exert a positive inotropic effect on the isolated rat heart by …

Urolithin B improves cardiac function and reduces susceptibility to ventricular arrhythmias in rats after myocardial infarction

H Gao, X Huang, Y Tong, X Jiang - European Journal of Pharmacology, 2020 - Elsevier
… ECG recordings revealed that MI-induced rats had a higher heart rate (HR) than rats in the
heart system to examine the inducibility of ventricular arrhythmias in three groups of rats. …

[HTML][HTML] Cardiac-specific CGI-58 deficiency activates the ER stress pathway to promote heart failure in mice

X Xie, YF Tie, S Lai, YL Zhang, HH Li, Y Liu - Cell Death & Disease, 2021 - nature.com
… exert essential regulatory effects on heart function. Comparative gene identification 58 (CGI-…
role in maintaining heart function. In this study, the effects of CGI-58 on heart function and …

[HTML][HTML] Water-soluble alkaloids extracted from Aconiti Radix lateralis praeparata protect against chronic heart failure in rats via a calcium signaling pathway

X Xu, X Xie, H Zhang, P Wang, G Li, J Chen… - Biomedicine & …, 2021 - Elsevier
… both rats and cultured cells [[18], [19], [20]]. However, the effects and mechanisms of AWAs
on chronic heart … The aim of the present study is to evaluate the effects of AWA extract in a rat

Effects of propofol on cardiomyocytes apoptosis and its mechanism after ischemia/reperfusion injury in isolated rat hearts

LJ Xie, JX Zhang, LF Li - Zhongguo Ying Yong Sheng li xue za zhi …, 2008 - europepmc.org
… Forty isolated perfused rat hearts were randomly divided into control, I/R, propofol 15, 30,
60 micromol x L(-1) groups. Hearts were suffered globally ischemia for 25 min and 30 min with …

Ginsenoside Re preserves cardiac function and ameliorates left ventricular remodeling in a rat model of myocardial infarction

Y Yu, J Sun, J Liu, P Wang, C Wang - Journal of Cardiovascular …, 2020 - journals.lww.com
… -β1 protein in rat heart. C, Expression of p-Smad2/3 and Smad2/3 protein in rat heart. GAPDH
was … Therefore, Gin-Re seems to have excellent cardioprotective effects in the MI rat heart. …

The effect of hyperoside on the functional recovery of the ischemic/reperfused isolated rat heart: potential involvement of the extracellular signal-regulated kinase 1/2 …

Z Li, J Hu, Y Li, F Xue, L Zhang, J Xie, Z Liu, H Li… - Free Radical Biology …, 2013 - Elsevier
… Using the Langendorff model, isolated Sprague–Dawley rat hearts were subjected to 30 …
We report for the first time that administration of Hyp before/after I/R significantly improved heart

Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy

M Xie, Y Kong, W Tan, H May, PK Battiprolu… - Circulation, 2014 - Am Heart Assoc
… Isolation and Culture of Primary Adult Rat Ventricular Myocytes Adult rat ventricular
myocytes (ARVMs) were isolated from hearts of male adult Sprague-Dawley rats (250–350 g). …