… in serum from healthy CD rats and noted changes in rats treated with … the proteome from both
liver and serum from CD rats was … by the Pfizer/OGS proteomics collaboration and identified …

… conventional approaches in preclinical toxicity screening, … rat liver showing druginduced
steatosis, respectively. These events were consistent with our observations on HSP60 in rat liver…

… (s) of hydrazine toxicity remain obscure. We sought to explore hydrazine hepatotoxicity
by a systematic proteomics approach, consisting of 2-D DIGE analysis of hydrazine-induced …

… a proteomics based approach to identify a toxicity marker. 163 and 321 proteins were identified
from the rat liver and the HepG2 proteome. … identified from the rat liver proteome and 314 …

… In the present study a proteomic approach is used to investigate toxic effects of ENA, A1,
B and B1 in rat liver after acute exposure. The samples were analyzed by quadrupole time-of-…

… measured by standardized photometric methods that can be … the liver also can be injured by
toxicants and provide toxicity … MS/MS) analyses of rat liver, mouse liver, rat liver endoplasmic …

… pathogenesis of rat liver fibrosis due to TAA-induced toxicity could … Finally, these proteomics
data and the data obtained from the … This is the first report in using a proteomics approach to …

… The optimized MRM liver (split in 2) and plasma methods were then … to liver toxicity pathways.
We then constructed MRM transition lists for proteotypic peptides based on the rat liver MS/…

… rat livers after oral administration of PM extracts based on the grey values. In addition, expression
of Slc16a2 was down-regulation in the rat livers … with the iTRAQ proteomics, indicating …

… Rat is a useful, widely used animal model for biological and toxicity studies. We analyzed
total and cytosolic rat liver proteins by applying proteomics technologies. The proteins were …