… with antimicrobial and … dual antimicrobial–anticancer activity, including advances in
computational biology using in silico analyses as a powerful tool for the study and rational design of …

… Also, the reported dual-functionalized implants often required the use of external stimuli,
including electricity 91 , light 75 , and temperature 92 , but our rationally designed dual-…

… , diblock amphiphilic molecules with antimicrobial and antifouling segments in a single chain
were rationally designed and synthesized. Cationic antimicrobial polypeptides (AMP) were …

… An alternative possibility is the the design of antimicrobial compounds that equipotently …
In the current work, we have rationally designed a novel series of antibacterial compounds, …

… Here, we report a rationally designed polymer, an oligoamidine, that selectively targets the
… As the first example of an antimicrobial homopolymer with a dual-selective mechanism of …

… This strategy aims to construct dual/multifunction hybrid … The theoretical basis for the design
of dual function and multi-… Design and activity of a ‘dual-targeted’ antimicrobial peptide. …

… Therefore, the amphiphilicity of AMPs is very critical in maintaining antimicrobial activity. …
I is an attractive target for the design of antimicrobial peptide drugs. Most proteins secreted by …

… The structural determinants relevant to antimicrobial activities of … Rational design of peptides
that are either present in nature … Tylotoin-sC18* displayed dual functions: antimicrobial and …

… IMPORTANCE In our in vitro studies, one dual stapled peptide out of the series of candidates
(TP4-3: FIIXKKSXGLFKKKAGAXKKKXIKK) showed significant activity, low toxicity, and …

… In this study, we further designed and modified cationic amphiphilic carbazole derivatives
for screening and identification of broad-spectrum antimicrobial compounds to overcome …