Selective loss of estrogen receptor β in malignant human colon

EF Foley, AA Jazaeri, MA Shupnik, O Jazaeri, LW Rice - Cancer Research, 2000 - AACR
… expression of ER-α and ER-β in normal colon and colon cancer samples from patients. ER-β
… Jazaeri O., Shupnik MA, Jazaeri AA, Rice LW Expression of estrogen receptor α mRNA and …

… receptor-α up-regulates hTNF-α gene expression and down-regulates β-catenin signaling activity to induce the apoptosis and inhibit proliferation of LoVo colon cancer …

HH Hsu, SF Cheng, LM Chen, JY Liu, CH Chu… - Molecular and cellular …, 2006 - Springer
… the expression of the TNF-α gene and the death receptor pathway to activate caspase 8
and … sis is central to the tumor-suppressive activity of p53 [30], and in most cases, p53-induced …

Synergistic effects of RXRα and PPARγ ligands to inhibit growth in human colon cancer cells—phosphorylated RXRα is a critical target for colon cancer management

K Yamazaki, M Shimizu, M Okuno… - Gut, 2007 - gut.bmj.com
Colon cancer and its surrounding non-cancerous colon tissues were obtained by surgical
resections from eight patients… the retinoid X receptor α (RXRα) protein in colon cancer cell lines …

Genetic variation in the retinoid X receptor and calcium-sensing receptor and risk of colorectal cancer in the Colon Cancer Family Registry

ET Jacobs, ME Martínez, PT Campbell… - …, 2010 - academic.oup.com
… for evaluation of MSI status for colorectal cancer cases (ACTC, BAT25, BAT26, BAT40,
BAT34C4, D5S346, D17S250, D18S55, D10S197 and MYCL). Cases were classified as MS …

Estrogen receptor β induces antiinflammatory and antitumorigenic networks in colon cancer cells

K Edvardsson, A Ström, P Jonsson… - Molecular …, 2011 - academic.oup.com
… Estrogen acts via two receptors, ie. estrogen receptor α (ERα) and estrogen receptor β (ERβ)…
Using ERβ as a prognostic marker in colon tumors may help to identify patients with a better …

IL-8 is involved in estrogen-related receptor α-regulated proliferation and migration of colorectal cancer cells

S Ding, Z Tang, Y Jiang, H Huang, P Luo… - Digestive diseases and …, 2017 - Springer
… [10] and associated with poor clinical outcome of cancer patients [11]. Inhibition of ERRα by
small interfering RNA (siRNA) or its inverse agonist XCT-790 can suppress growth of breast …

Estrogen receptor beta as target for colorectal cancer prevention

C Williams, A DiLeo, Y Niv, JÅ Gustafsson - Cancer letters, 2016 - Elsevier
Cases included a series of patients with histologically … as cases except for not having a
diagnosis of colorectal cancer. … that the risk of colon cancer, but not rectal cancer, increased with …

Oestrogen receptor-related receptor alpha (ERRα) and oestrogen receptors (ERα and ERβ) exhibit different gene expression in human colorectal tumour progression

A Cavallini, M Notarnicola, R Giannini… - … journal of cancer, 2005 - Elsevier
receptors in samples of colorectal adenocarcinoma matched with surrounding normal mucosa
of eighty patients. … of ERβ proteins and degree of colorectal cancer cell differentiation by …

Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARγ-coactivator 1 (PGC-1)

J Feilchenfeldt, MA Bründler, C Soravia, M Tötsch… - Cancer letters, 2004 - Elsevier
receptor α (RXRα) and PPARγ-coactivator-1 (PGC-1) by means of real-time PCR in 17 patients
with colon cancer… observed for the expression level of the PPAR-isoforms α,β/δ and γ, the …

Prognostic value of estrogen receptor-α and progesterone receptor in curatively resected colorectal cancer: a retrospective analysis with independent validations

SB Ye, YK Cheng, L Zhang, XP Wang, L Wang, P Lan - BMC cancer, 2019 - Springer
… Most of the patients with stage II-III rectal cancer received radiotherapy. 5-FU based
chemotherapy was delivered concurrently with radiation in forms of three-dimensional conformal …