… This strategy revealed that agonists with pharmacology to TLR3, TLR4 and TLR7 activated
… receptor target for Imiquimod. This implies that all of the functional responses mediated by …

… agonists induced a robust response in HNSCCs, characterized by generation of inflammation
and cell … Moreover, the epithelial cell activation in response to Pam 3 CSK 4 , poly(I:C) and …

… receptors in BEAS-2B cells and PBEC and perform microarray analysis of epithelial gene
expression in response to TLR agonists. Assessment of TLR mRNA expression in BEAS-2B …

… but fail to generate a signal after binding the receptor. These … cells or damaged tissues.
The chronic activation of TLRs exerted by DAMPs may stimulate T- and B-cells responses and, …

… A surprising finding in the CHOA1H cells was the residual amplification of ATP responses
by A 1 receptor agonists after overnight treatment with PTX (Fig. 7 and Table 5). These data …

… Several mIL-2Q141 substitution proteins are partial agonists since they fail to elicit maximal
cellular responses at receptor-saturating concentrations (Zurawski et al., 1990). Furthermore, …

… It is likely that dietary intakes of most phytochemicals would be below levels required for
an AhR agonist response based on results from cell culture studies. The potential …

… receptor turnover is accelerated in proportion to the agonist concentration in order to allow
the cells to produce an adapted cellular response to … a key role in cell sensitivity to hormones. …

… Dendritic cells (DCs), a highly specialized antigen-presenting cell (APC) system critical for
the initiation of CD4 + T-cell responses, are present in different stages of maturation in the …

… To test the effectiveness of J4 and F4 at enhancing antigen-specific CD8 + T cell responses,
we stimulated PBMCs from healthy donors with either J4 or F4 in the presence of 0.001 μM …