Bioactive supramolecular peptide nanofibers for regenerative medicine

E Arslan, IC Garip, G Gulseren… - Advanced …, 2014 - Wiley Online Library
… In this respect, supramolecular peptide nanofibers have … , self-assembled peptide
nanofiber systems have a special … synthesis methods associated with peptide nanofibers, and …

A combined carrier-adjuvant system of peptide nanofibers and toll-like receptor agonists potentiates robust CD8+ T cell responses

JS Rudra, BN Banasik, GN Milligan - Vaccine, 2018 - Elsevier
peptide nanofibers presenting an immunodominant antigen from herpes simplex virus (HSV)
and toll-like receptor (TLR) agonists that … by the type of TLR agonist. The use of CpG (TLR9 …

Peptide nanofibers: targeted therapies for glioblastoma multiforme

DM Leite, R Zhu, E Barbu, P Hinterdorfer, GJ Pilkington… - Cancer Research, 2017 - AACR
… (GPCRs) that when activated by neuropeptide agonists result in an antiproliferative effect. …
of peptide agonists which results in peptide amphiphiles able to self-assemble into nanofibers

Nanofiber-based delivery of therapeutic peptides to the brain

M Mazza, R Notman, J Anwar, A Rodger, M Hicks… - ACS …, 2013 - ACS Publications
… dalargin (Tyr-d-Ala-Gly-Phe-Leu-Arg), an opioid receptor agonist, … the peptide moieties
makes the nanofibers less prone to dissolution in the plasma and would also protect the peptide

Self‐assembling peptide nanofiber hydrogels in tissue engineering and regenerative medicine: progress, design guidelines, and applications

S Koutsopoulos - … of Biomedical Materials Research Part A, 2016 - Wiley Online Library
… The discovery of short self‐assembling peptides, which upon … , peptide self‐assembly leads
to the formation of nanofibers, … peptides which self‐assemble to form nanofiber hydrogels …

Self-assembled peptide nanofibers raising durable antibody responses against a malaria epitope

JS Rudra, S Mishra, AS Chong, RA Mitchell, EH Nardin… - Biomaterials, 2012 - Elsevier
… To develop a better understanding of the immune responses associated with self-assembling
peptides, we sought to investigate the mechanisms through which Q11 nanofibers activate …

Active immunotherapy for TNF-mediated inflammation using self-assembled peptide nanofibers

C Mora-Solano, Y Wen, H Han, J Chen, AS Chong… - Biomaterials, 2017 - Elsevier
nanofibers, and the T-cell response was focused on exogenous and non-autoreactive T-cell
epitopes. Immunization with unadjuvanted peptide nanofibers … with peptide nanofibers did …

Multiepitope supramolecular peptide nanofibers eliciting coordinated humoral and cellular antitumor immune responses

Y Wu, H Wen, ZJ Bernstein, KM Hainline… - Science …, 2022 - science.org
… responses (30, 35), so to generate T H 1-biased humoral responses for antitumor efficacy,
we additionally used CpG, a Toll-like receptor 9 (TLR9) agonist (46–48), as an adjuvant in all …

A Self-Assembling Lipidic Peptide and Selective Partial V2 Receptor Agonist Inhibits Urine Production

S Patel, AB Volpe, S Awwad, AG Schätzlein… - Scientific Reports, 2020 - nature.com
… We sought to examine if a lipidized peptide, which assembles into nanofibers could serve
as a selective V2 receptor agonist and control urine production. Such a compound may serve …

Nanofiber-based sutures induce endogenous antimicrobial peptide

S Chen, L Ge, AF Gombart, FD Shuler, MA Carlson… - …, 2017 - Taylor & Francis
… 3 and pam3CSK4 peptide in PCL/F-127 nanofiber-based sutures … of 25D 3 and pam3CSK4
peptide from nanofiber-based sutures … The pam3CSK4 peptide, a TLR2/1 receptor agonist, is …