Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease.

A Mizoguchi, E Mizoguchi, C Chiba… - The Journal of …, 1996 - rupress.org
… an ulcerative colitis (UC)l-like inflammatory bowel disease (IBD) (7, 10). Compared to other
autoimmune diseases, the etiological factors of UC, an organ-specific autoimmune disease, …

[HTML][HTML] Role of cytokines in inflammatory bowel disease

F Sanchez-Muñoz, A Dominguez-Lopez… - World journal of …, 2008 - ncbi.nlm.nih.gov
… been noted in the inflamed gut of patients with IBD. … inflammatory cytokines in the gut, and
imbalance of cytokines is contributing to the pathogenesis of IBD. The intestinal inflammation

Immunoregulatory pathways involved in inflammatory bowel disease

G Fonseca-Camarillo… - Inflammatory bowel …, 2015 - academic.oup.com
Crohn's disease. The immune response in ulcerative colitis is different from the Crohn's
disease… that IBD results from an inappropriate inflammatory response to intestinal microbes in a …

[HTML][HTML] Study of tumor necrosis factor receptor in the inflammatory bowel disease

RF Souza, MAF Caetano, HIR Magalhães… - World Journal of …, 2023 - ncbi.nlm.nih.gov
… of Tumor Necrosis Factor-alpha (TNF-α) in promoting inflammation. Studies have suggested
… pro-inflammatory cytokines involved in the pathogenesis of Inflammatory Bowel Diseases (…

[HTML][HTML] … of endogenous and exogenous ligands for the peroxisome proliferators activated receptors alpha (PPAR-α) in the development of inflammatory bowel disease …

S Cuzzocrea, R Di Paola, E Mazzon… - Laboratory …, 2004 - nature.com
colitis. Thus, endogenous and exogenous PPAR-α ligands reduce the degree of colitis
propose that PPAR-α ligand may be useful in the treatment of inflammatory bowel disease. …

The genetics and immunopathogenesis of inflammatory bowel disease

JH Cho - Nature Reviews Immunology, 2008 - nature.com
… , notably IL23R (encoding interleukin-13 receptor), IL12B (encoding the p40 subunit for IL-12
and IL-23) and STAT3 (encoding signal transducer and activator of transcription 3), all of …

Cytokines in inflammatory bowel disease

AC Moldoveanu, M Diculescu… - Romanian Journal of …, 2015 - sciendo.com
… role in the pathogenesis of inflammatory bowel diseases. The … paradigms in inflammatory
bowel diseases has been done on … inflammatory bowel disease in T cell receptor alpha chain-…

Role of the xenobiotic receptor in inflammatory bowel disease

R Arsenescu, V Arsenescu, J Zhong… - Inflammatory bowel …, 2011 - academic.oup.com
… Gene-environment interplay modulates inflammatory bowel diseases (IBD). Dioxin-like
compounds can activate the aryl hydrocarbon receptor (AhR) and alter macrophage function as …

The genetics of inflammatory bowel disease

JH Cho, CT Weaver - Gastroenterology, 2007 - gastrojournal.org
The inflammatory bowel diseases (IBDs) are subdi-vided into Crohn’s disease (CD) and
ulcerative colitis (UC) based on well-established clinical and pathologic criteria. Recently, …

Nuclear receptors in the pathogenesis and management of inflammatory bowel disease

L Ning, X Lou, F Zhang, G Xu - Mediators of inflammation, 2019 - Wiley Online Library
… Previous epidemiological and genetic studies have documented the association of NRs
with the risk of inflammatory bowel disease (IBD). Although the mechanisms of action of NRs in …