… antibody was reported (3), and it demonstrated that the stimulating antibody bound to the
leucine-rich domain of the receptor. … indeed detect TRAb with high sensitivity and specificity. …

… affinity of the Abs used in the receptor unit. Since sensitivity is directly related to the affinity
of the ligand binding, reversibility excludes high sensitivity. Consequently, detection units for …

… very high sensitivity of the cell-based bio-assays for the diagnosis of autoimmune induced
hyper- and hypothyroidism and clearly shows the detection of all samples at very low antibody …

… The better signal to noise ratio leads to a lower decision threshold for the cut-off and increases
the sensitivity, as shown by ROC plot analysis. For clinical purposes this high sensitivity …

… In conclusion, both assays had a high sensitivity and specificity for diagnosing GD. hTSHR-Ab
values were in average 2.5 times higher with the bTSH-rhTSHR assay compared with the …

… sensitivity and specificity. With the newer third generation TRAb assays, it is possible to
identify patients with high to very high … Thyroid stimulating hormone receptor autoantibody titer …

… that the antibody under investigation has the sensitivity to detect CB2 protein when the
receptor is expressed in sufficient abundance along with evidence that the antibody also labels …

… In summary, the proposed high sensitivity of the new TBII assay using human recombinant
TSH-R could be confirmed with the commercial product. This method offers a clear advantage …

… anti-receptor antibody in the serum. ProteinA linkedto agarose beads may be substituted for
the second antibody … and hyperinsulinemia, but with normal sensitivity to exogenous insulin. …

… show requisite clinical sensitivity and high specificity with … bioas-says might be more sensitive
for diagnosing subtle disease. … have demonstrated a higher sensitivity for detecting TSH-R-…