… For a more permissive analysis, we also offer a simpler filtering method based on a threshold
of cells expressing ligand–receptor complexes in the corresponding clusters. In addition, …

… receptor (EGFR) represents the paradigm for cross-talk between G protein-coupled receptors
(GPCRs) and receptor … new components of a cellular communication network of rapidly …

… ligand-receptor interaction database. CellChatDB takes into account known composition
of the ligand-receptor complexes, including complexes with multimeric ligands and receptors, …

… store ligand-receptor pairs. The recently applications and research tools of ligand-receptor
interactions for cell communication at single cell level by using single cell RNA sequencing …

… and receptors active in cell communication. As mRNAs encoding surface receptors frequently
show low abundance, this strategy better accounts for the variance in receptor expression. …

… level in cells (21), and mRNAs encoding some surface receptors usually show low … receptors
not being detected at the single-cell level (16,22). More importantly, cell-cell communication …

… Cell-cell communication is a key aspect of dissecting the complex cellular microenvironment.
Existing single-cell and spatial transcriptomics-based methods primarily focus on …

… Coactivators and corepressors are essential for steroid receptor modulation of gene expression.
These large proteins form complexes with the activated steroid receptor family. Some of …

… understanding of cellular communication in the brain, how drugs act on the brain and how
this communication is … It gave the beginning of a cellular basis for neuropsychopharmacology. …

… communication. RRIs, indeed, allow GPCR to operate not only as monomers but also as
receptor complexes, … of the protomers forming the complex. The main biochemical mechanisms …