TALKIEN: crossTALK IntEraction Network. A web-based tool for deciphering molecular communication through ligand–receptor interactions
F Moratalla-Navarro, V Moreno, R Sanz-Pamplona - Molecular Omics, 2023 - pubs.rsc.org
… drugs targeting receptors. In conclusion, TALKIEN allows users to detect ligand–receptor
interactions generating new in silico predictions of cell–cell communication thus providing a …
interactions generating new in silico predictions of cell–cell communication thus providing a …
CellCallEXT: analysis of ligand–receptor and transcription factor activities in cell–cell communication of tumor immune microenvironment
… CellCall is an R package tool that is used to analyze cell–cell communication based on
transcription factor (TF) activities calculated by cell-type specificity of target genes and thus …
transcription factor (TF) activities calculated by cell-type specificity of target genes and thus …
Epidermal growth factor receptor: elements of intracellular communication
SMT Hernández-Sotomayor, G Carpenter - The Journal of membrane …, 1992 - Springer
… cell surface with which EGF interacts: the EGF receptor. The remainder of this review will focus
on the EGF receptor… as the best understood example of a single transmembrane receptor. …
on the EGF receptor… as the best understood example of a single transmembrane receptor. …
Extracting intercellular signaling network of cancer tissues using ligand-receptor expression patterns from whole-tumor and single-cell transcriptomes
JX Zhou, R Taramelli, E Pedrini, T Knijnenburg… - Scientific Reports, 2017 - nature.com
… From single-cell RNA-Seq data for a case of melanoma … -receptor interactions and their
gene expression measured in individual cells, we constructed a map of a cell-cell communication …
gene expression measured in individual cells, we constructed a map of a cell-cell communication …
Receptor mosaics of neural and immune communication: possible implications for basal ganglia functions
LF Agnati, KG Fuxe, LB Goncharova… - Brain research reviews, 2008 - Elsevier
… Receptor assemblies seem to play a key role in the integration and modulation of molecular
signals of cell–cell communications. This may be confirmed by recent discoveries of the …
signals of cell–cell communications. This may be confirmed by recent discoveries of the …
Hormone receptor complexes and their modulation of membrane function
P Cuatrecasas, MD Hollenberg, KJ Chang… - Proceedings of the 1974 …, 1975 - Elsevier
… This suggestion was made on the basis of the observation that the spontaneous rate of
dissociation of the hormone–receptor complex was accelerated by the addition of native insulin …
dissociation of the hormone–receptor complex was accelerated by the addition of native insulin …
Receptor action and interaction
AM de Vos, AA Kossiakoff - Current Opinion in Structural Biology, 1992 - Elsevier
… ltow cells communicate is one of the most intriguing issues in cell biology. Most of the
communication is thought to be mediated through cell-surface receptors, initiated by a ligand …
communication is thought to be mediated through cell-surface receptors, initiated by a ligand …
[HTML][HTML] Gap junctional complexes: from partners to functions
JC Hervé, N Bourmeyster, D Sarrouilhe… - Progress in biophysics …, 2007 - Elsevier
… Gap junctions (GJ), specialised membrane structures that mediate cell-to-cell communication
in … Receptor protein tyrosine phosphatases (RPTPs) form a family of cell-surface receptors …
in … Receptor protein tyrosine phosphatases (RPTPs) form a family of cell-surface receptors …
The TNF family of ligands and receptors: communication modules in the immune system and beyond
C Dostert, M Grusdat, E Letellier… - Physiological …, 2019 - journals.physiology.org
… The THD is responsible for the trimerization of TNF ligands (see below) and their binding to
the trimerized receptor complex (43, 254). TNF ligands are usually synthesized in membrane-…
the trimerized receptor complex (43, 254). TNF ligands are usually synthesized in membrane-…
Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia
L Homolya, TH Steinberg, RC Boucher - The Journal of cell biology, 2000 - rupress.org
… Using a combination of approaches, including enzymes that destroy extracellular
nucleotides, purinergic receptor desensitization, and airway cells deficient in purinoceptors, we …
nucleotides, purinergic receptor desensitization, and airway cells deficient in purinoceptors, we …