… receptor complexes and their allosteric receptor-receptor interactions in the plasma membrane represent a new biological principle for integration of signals in the …

DO Borroto-Escuela, K Fuxe - Frontiers in molecular neuroscience, 2019 - frontiersin.org
… and monoamine signals in the Central Nervous System (CNS) could become integrated
in the plasma membrane through direct peptide receptor-monoamine receptor interactions (…

SIGNALING AT THE GROWTH CONE: Ligand-Receptor Complexes and the Control of Axon Growth and Guidance

AB Huber, AL Kolodkin, DD Ginty… - Annual review of …, 2003 - annualreviews.org
… The guidance of axons during the establishment of the nervous system is mediated by a …
cell-surface receptors have now been identified, and the intracellular signaling pathways by …

Axon guidance: receptor complexes and signaling mechanisms

IC Grunwald, R Klein - Current opinion in neurobiology, 2002 - Elsevier
… Ligand activities are transduced by receptors and their signaling effectors. … of receptor
crosstalk and signaling mechanisms. … of semaphorin signaling in the mammalian nervous system. …

The tripartite CNTF receptor complex: activation and signaling involves components shared with other cytokines

N Stahl, GD Yancopoulos - Journal of neurobiology, 1994 - Wiley Online Library
… limited to cells of the nervous system. Nevertheless, CNTF utilizes identical … receptors in
general. Analysis of intracellular signaling pathways activated by the CNTF receptor complex

G protein-coupled receptor signaling complexity in neuronal tissue: implications for novel therapeutics

S Maudsley, B Martin, LM Luttrell - Current Alzheimer Research, 2007 - ingentaconnect.com
central nervous system (CNS), receptor signaling specificity and diversity has facilitated the
creation of an unimaginably complex … the CNS consists of a small number of basic signaling

Glutamatergic signaling in the central nervous system: ionotropic and metabotropic receptors in concert

A Reiner, J Levitz - Neuron, 2018 - cell.com
… both receptor families with a focus on their crosstalk, we argue for a more holistic understanding
of neural glutamate signaling. … To accommodate the complex roles of glutamate as a …

Neurotrophins and their receptors: signaling trios in complex biological systems

KK Teng, BL Hempstead - Cellular and Molecular Life Sciences CMLS, 2004 - Springer
… In recent studies, p75NTR has been identified as a component of the Nogo receptor complex,
as Nogo and p75NTR biochemically interact [36, 37] and as misexpression of p75NTR …

Cytokines that signal through the leukemia inhibitory factor receptor‐β complex in the nervous system

AM Turnley, PF Bartlett - Journal of neurochemistry, 2000 - Wiley Online Library
… molecules that signal via binding to a glycoprotein 130 (gp 130) cytokine receptor complex,
… a leukemia inhibitory factor receptor-β (LIFRβ)/gp130 complex, either with or without a third …

Signals and receptors

CH Heldin, B Lu, R Evans… - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
… II receptors into heterotetrameric receptor complexes, in which constitutively active type II
receptors phosphorylate type I receptors in … In the TGFβ type I receptor, this causes a change in …

Crosstalk between receptor tyrosine kinases (RTKs) and G protein-coupled receptors (GPCR) in the brain: Focus on heteroreceptor complexes and related functional …

V Di Liberto, G Mudò, N Belluardo - Neuropharmacology, 2019 - Elsevier
… resulting in RTKs transactivation and in growth-promoting signals. In this review, we describe
heteroreceptor complexes between GPCR and RTKs in the central nervous system (CNS) …