Regulation of androgen receptor levels: implications for prostate cancer progression and therapy
KL Burnstein - Journal of cellular biochemistry, 2005 - Wiley Online Library
… recurrent prostate cancer and discusses the multiple mechanisms that regulate AR levels in
… new drug targets for modulating levels of this receptor, a key signaling molecule in prostate …
… new drug targets for modulating levels of this receptor, a key signaling molecule in prostate …
Androgen receptors in prostate cancer
… In the last decade research on androgen receptor (AR) in prostate cancer led to … in cancer
tissue and disease outcome. AR binding assays were not routinely used in prostate cancer …
tissue and disease outcome. AR binding assays were not routinely used in prostate cancer …
Androgen receptors in prostate cancer.
… prostate cancer but not because of prostate cancer. It is hoped that application of new
technologies in prostate cancer … in the early stages of prostate cancer. Hormonal dependence of …
technologies in prostate cancer … in the early stages of prostate cancer. Hormonal dependence of …
Androgen receptor in prostate cancer
CA Heinlein, C Chang - Endocrine reviews, 2004 - academic.oup.com
… remain important in prostate cancer. Approximately 80–90% of prostate cancers are
dependent on androgen at initial diagnosis, and endocrine therapy of prostate cancer is directed …
dependent on androgen at initial diagnosis, and endocrine therapy of prostate cancer is directed …
Androgen receptor signaling in prostate cancer
… receptor coactivators (SRC) in prostate cancer. The expression of SRC-1 correlates with
prostate cancer … and mediates the ligand-independent activation of the receptor by IL-6 [84, 85]. …
prostate cancer … and mediates the ligand-independent activation of the receptor by IL-6 [84, 85]. …
Low stroma androgen receptor level in normal and tumor prostate tissue is related to poor outcome in prostate cancer patients
P Wikström, J Marusic, P Stattin, A Bergh - The Prostate, 2009 - Wiley Online Library
… The role of androgen receptors (ARs) in the prostate tumor cell environment is largely … ,
tumor characteristics and clinical outcome in normal and prostate cancer (PCa) tissue obtained at …
tumor characteristics and clinical outcome in normal and prostate cancer (PCa) tissue obtained at …
Androgen receptor levels are upregulated by Akt in prostate cancer
S Ha, R Ruoff, N Kahoud, TF Franke… - … -related cancer, 2011 - erc.bioscientifica.com
… that AR protein levels are not decreased in all androgen-independent prostate cancer cells
… of Akt inhibitors in some late-stage prostate cancers. This is supported by studies showing …
… of Akt inhibitors in some late-stage prostate cancers. This is supported by studies showing …
Androgen receptor levels in prostate cancer epithelial and peritumoral stromal cells identify non‐organ confined disease
C Ricciardelli, CS Choong, G Buchanan… - … Prostate, 2005 - Wiley Online Library
… In summary, this study of clinically localized prostate cancer has demonstrated that high
levels of AR in malignant epithelial cells and a reduction of AR positive nuclear area in …
levels of AR in malignant epithelial cells and a reduction of AR positive nuclear area in …
Hormonal regulation of β2‐adrenergic receptor level in prostate cancer
H Ramberg, T Eide, KA Krobert, FO Levy… - … Prostate, 2008 - Wiley Online Library
… - and protein levels when hormone-sensitive prostate cancer cells, … The number of β-adrenergic
receptors was modestly up-… Triiodothyronine (T3) increased the level of β2-AR and the …
receptors was modestly up-… Triiodothyronine (T3) increased the level of β2-AR and the …
The androgen receptor in prostate cancer
J Trapman, AO Brinkmann - Pathology-Research and Practice, 1996 - Elsevier
… prostate tumors show high levels of androgen receptor … ar localization of the androgen
receptor suggests that it is in an … prostate cancer, the androgen receptor expression level …
receptor suggests that it is in an … prostate cancer, the androgen receptor expression level …
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