Epidermal growth factor receptor mutations in lung cancer

SV Sharma, DW Bell, J Settleman, DA Haber - Nature Reviews Cancer, 2007 - nature.com
… Like most cancers, lung cancer is a conglomeration … -cell lung cancer (SCLC, comprising
20% of lung cancers), and non-small-cell lung cancer (NSCLC, comprising 80% of lung cancers

Epidermal growth factor receptor mutations in patients with non–small cell lung cancer

BE Johnson, PA Jänne - Cancer research, 2005 - AACR
… growth factor receptor mutation in non-small-cell lung cancer patients treated with gefitinib.
… EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and …

Epidermal growth factor receptor mutations in small cell lung cancer

A Tatematsu, J Shimizu, Y Murakami, Y Horio… - Clinical Cancer …, 2008 - AACR
mutations have recently been reported in some patients with small cell lung cancers (SCLC)…
In this study, we first examined a large series of SCLCs to address mutation incidence. …

Epidermal growth factor receptor mutations in non–small-cell lung cancer: Implications for treatment and tumor biology

PA Jänne, JA Engelman, BE Johnson - Journal of clinical oncology, 2005 - ascopubs.org
… The epidermal growth factor receptor (EGFR) has emerged as an attractive therapeutic
target for patients with non–small-cell lung cancer (NSCLC). However, despite its almost …

Screening for epidermal growth factor receptor mutations in lung cancer

R Rosell, T Moran, C Queralt, R Porta… - … England Journal of …, 2009 - Mass Medical Soc
… We prospectively screened 2105 patients with non–small-cell lung cancer for EGFR mutations.
Patients with mutations were then considered for erlotinib treatment at a dose of 150 mg …

The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non–small cell lung cancers

M Tokumo, S Toyooka, K Kiura, H Shigematsu… - Clinical cancer …, 2005 - AACR
lung cancers are classified into two major types, small cell lung cancer (SCLC) and non–small
cell lung cancer (… adenocarcinoma and squamous cell carcinoma. Previously, squamous …

Detection of Mutations in EGFR in Circulating Lung-Cancer Cells

S Maheswaran, LV Sequist, S Nagrath… - … England Journal of …, 2008 - Mass Medical Soc
… the epidermal growth factor receptor gene (EGFR) in patients with non–small-cell lung
non–small-cell lung cancers previously identified as having the EGFR mutation and 8 specimens …

Update on Epidermal Growth Factor Receptor Mutations in Non–Small Cell Lung Cancer

GJ Riely, KA Politi, VA Miller, W Pao - Clinical Cancer Research, 2006 - AACR
… in patients with non–small cell lung cancer. Since then, multiple groups … mutations confer
as well as the clinical relevance of these mutations in patients with non–small cell lung cancer. …

Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non–small-cell lung cancer: current knowledge and future directions

W Pao, VA Miller - Journal of Clinical Oncology, 2005 - ascopubs.org
Mutations in non–small-cell lung cancers have been found in [1] epidermal growth factor
receptor … Only EGFR tyrosine kinase domain mutations are associated with sensitivity to gefitinib …

[HTML][HTML] Worldwide prevalence of epidermal growth factor receptor mutations in non-small cell lung cancer: a meta-analysis

B Melosky, K Kambartel, M Haentschel… - Molecular Diagnosis & …, 2022 - Springer
… growth factor receptor (EGFR) gene mutations in non-small cell lung cancer (NSCLC) is …
This meta-analysis was conducted to provide a worldwide overview of EGFR mutation and …