Efficacy of gefitinib for non‐adenocarcinoma non‐small‐cell lung cancer patients harboring epidermal growth factor receptor mutations: A pooled analysis of …

T Shukuya, T Takahashi, R Kaira, A Ono… - Cancer …, 2011 - Wiley Online Library
… regimens for small-cell lung cancer (SCLC) and NSCLC. … Epidermal growth factor
receptor mutations can be detected … ( 5 ) Epidermal growth factor receptor mutations can be …

Mutations in the tyrosine kinase domain of the epidermal growth factor receptor in non–small cell lung cancer

SH Yang, LE Mechanic, P Yang, MT Landi… - Clinical cancer …, 2005 - AACR
… , and ethnic or geographic features among lung cancer patients. We therefore evaluated …
contributions to lung cancer. Our aim was to assess the overall frequency of EGFR mutations in …

Epidermal growth factor receptor mutations in plasma DNA samples predict tumor response in Chinese patients with stages IIIB to IV non–small-cell lung cancer

H Bai, L Mao, HS Wang, J Zhao, L Yang… - Journal of Clinical …, 2009 - ascopubs.org
… Epidermal growth factor receptor mutations in exons 19 and 21 detected by … mutations
in non–small-cell lung cancer: (a) wild-type; (bg) 15– or 18–base pair deletion mutations

Epidermal growth factor receptor tyrosine kinase inhibitors in lung cancer: impact of primary or secondary mutations

A Sakurada, FA Shepherd, MS Tsao - Clinical lung cancer, 2006 - Elsevier
… of the National Cancer Institute of Canada … -cell lung cancer that had failed to respond to
first- or second-line chemotherapy provides new treatment options for patients with lung cancer

Impact of EGFR mutation analysis in non-small cell lung cancer

H Yamamoto, S Toyooka, T Mitsudomi - Lung cancer, 2009 - Elsevier
… The discovery of mutations in the tyrosine kinase domain of the epidermal growth factor
receptor (EGFR) gene in non-small cell lung cancer (NSCLC) accelerated the research of …

Deregulated EGFR Signaling during Lung Cancer Progression: Mutations, Amplicons, and Autocrine Loops

AF Gazdar, JD Minna - Cancer Prevention Research, 2008 - AACR
cancers. This selectivity was dramatically highlighted by the finding of EGFR tyrosine kinase
domain mutations, but lung cancer … EGFR pathway in driving lung cancer pathogenesis. Of …

Epidermal growth factor receptor mutations in non–small cell lung cancer: predicting clinical response to kinase inhibitors

LV Sequist, DA Haber, TJ Lynch - Clinical Cancer Research, 2005 - AACR
… growth factor receptor mutation in non-small-cell lung cancer patients … lung cancer (NSCLC)
cell lines associates with mutation and amplification of the epidermal growth factor receptor (…

Correlation between epidermal growth factor receptor mutations and the expression of estrogen receptor-β in advanced non-small cell lung cancer

F Deng, M Li, WL Shan, LT Qian… - Oncology …, 2017 - spandidos-publications.com
lung cancer, ~25% of lung cancer cases are not attributable to tobacco use (3). The increase
in lung cancer … in the prevalence of non-small cell lung cancer (NSCLC). NSCLC is more …

[HTML][HTML] Polymorphisms, Mutations, and Amplification of the EGFR Gene in Non-Small Cell Lung Cancers

M Nomura, H Shigematsu, L Li, M Suzuki… - PLoS …, 2007 - journals.plos.org
… We also obtained 93 DNA samples from non-malignant lung tissue of European-descent
patients with lung cancer in Italy and 250 DNA samples of peripheral blood mononuclear cells (…

Rare and complex mutations of epidermal growth factor receptor, and efficacy of tyrosine kinase inhibitor in patients with non-small cell lung cancer

B Keam, DW Kim, JH Park, JO Lee, TM Kim… - International journal of …, 2014 - Springer
mutations in the epidermal growth factor receptor (EGFR) gene in non-small cell lung cancer
(NSCLC) other than the two classical mutations of L858R and exon 19 deletional mutation. …