Cetuximab response of lung cancer–derived EGF receptor mutants is associated with asymmetric dimerization
… Given that several lung cancer-derived mutants of … receptor autophosphorylation. However,
immunoblotting and immunohistochemistry show that cetuximab treatment of lung cancers …
immunoblotting and immunohistochemistry show that cetuximab treatment of lung cancers …
CT characteristics of non-small cell lung cancer with epidermal growth factor receptor mutation: a systematic review and meta-analysis
Z Cheng, F Shan, Y Yang, Y Shi, Z Zhang - BMC Medical Imaging, 2017 - Springer
Background To systematically investigate the relationship between CT morphological features
and the presence of epidermal growth factor receptor (EGFR) mutations in non-small cell …
and the presence of epidermal growth factor receptor (EGFR) mutations in non-small cell …
HER2 mutations in lung adenocarcinomas: A report from the Lung Cancer Mutation Consortium
RN Pillai, M Behera, LD Berry, MR Rossi, MG Kris… - Cancer, 2017 - Wiley Online Library
… The Cancer Genome Project published what to our knowledge is the … mutations of HER2 in
lung cancers in 2004.19 Sequencing of HER2 in 120 lung tumors revealed somatic mutations …
lung cancers in 2004.19 Sequencing of HER2 in 120 lung tumors revealed somatic mutations …
Epidermal growth factor receptor mutations in non-small cell lung cancer: a basic science discovery with immediate clinical impact
JE Dowell, NM Caplan, BF Palmer - The American journal of the medical …, 2006 - Elsevier
… Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United …
States, lung cancer accounts for more deaths than breast, colon, prostate, and pancreas cancers …
States, lung cancer accounts for more deaths than breast, colon, prostate, and pancreas cancers …
Epidermal growth factor receptor mutations are associated with gefitinib sensitivity in non-small cell lung cancer in Japanese
H Uramoto, K Sugio, T Oyama, K Ono, M Sugaya… - Lung cancer, 2006 - Elsevier
… To determine whether lung tumors sensitive to gefitinib contained mutations … lung cancer
(NSCLC) who had been treated with gefitinib. Nine (45%) tumors had TK domain mutations. All …
(NSCLC) who had been treated with gefitinib. Nine (45%) tumors had TK domain mutations. All …
Association between hormone receptor expression and epidermal growth factor receptor mutation in patients operated on for non-small cell lung cancer
H Sun, Y Zheng, W Ou, Q Fang, P Li, X Ye… - The Annals of thoracic …, 2011 - Elsevier
… of ER and PR expression in lung cancers, but the … receptor expression and clinicopathologic
factors and epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer …
factors and epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer …
Mechanistic insights into acquired drug resistance in epidermal growth factor receptor mutation‐targeted lung cancer therapy
H Ji - Cancer science, 2010 - Wiley Online Library
… ; or cancer genetic alteration, which may be dependent on the therapeutics methods and
treatment duration. As cancer stroma plays an essential role in lung … in a non‐cancer‐cell‐…
treatment duration. As cancer stroma plays an essential role in lung … in a non‐cancer‐cell‐…
… growth factor receptor tyrosine kinase domain mutations on the outcome of patients with non–small cell lung cancer treated with epidermal growth factor receptor …
PA Jänne, BE Johnson - Clinical cancer research, 2006 - AACR
… Somatic mutations in the epidermal growth factor receptor (EGFR) have been identified
in patients with advanced non–small cell lung cancer who achieve dramatic clinical and …
in patients with advanced non–small cell lung cancer who achieve dramatic clinical and …
Comparison of epidermal growth factor receptor mutations between primary tumors and lymph nodes in non-small cell lung cancer: a review and meta-analysis of …
F Wang, P Fang, DY Hou, ZJ Leng… - … Pacific Journal of Cancer …, 2014 - koreascience.kr
… receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) can predict the clinical
response to tyrosine kinase inhibitor (TKI) therapy. However, EGFR mutations … EGFR mutations …
response to tyrosine kinase inhibitor (TKI) therapy. However, EGFR mutations … EGFR mutations …
A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations
H Asahina, K Yamazaki, I Kinoshita, N Sukoh… - … journal of cancer, 2006 - nature.com
… Twenty patients (24%) had EGFR mutations (deletions in or near E746-A750, n=16;
L858R, n=4). Epidermal growth factor receptor mutation status and patient clinicopathological …
L858R, n=4). Epidermal growth factor receptor mutation status and patient clinicopathological …