… growth factor receptor kinase activity via an intramolecular … of the epidermal growth
factor receptor tyrosine protein kinase in the absence of receptor …

… Such oncogenic homologs provide invaluable clues to the mechanisms of normal growth
factor receptors, in addition to enhancing our understanding of cellular transformation and …

… growth factor (EGF) receptor tyrosine kinase with a 5-pM inhibition constant. The inhibitor was
specific for the EGF receptor tyrosine kinase and inhibited other purified tyrosine … receptor …

… The interactions between the two homodimers within the context of a heterotetramer could
serve to stabilize the formation of one dimer indirectly by growth factor binding. For example, …

… from tyrosine kinases in the initiation, growth and metastases of many human tumours.[1]
Among the best studied of the receptor tyrosine kinases is the epidermal growth factor receptor (…

… A new growth factor receptor tyrosine kinase (RTK) … tyrosine kinase domains that flank the
insert domain, characteristic of known type III RTKs [eg platelet-derived growth factor receptor (…

… All receptor tyrosine … tyrosine kinase, distinct regulatory sequences with tyrosine, serine,
and threonine phosphorylation sites. The tyrosine kinase activity of growth factor receptors is …

… Trans-membrane receptor tyrosine kinases play an important role in the modulation of
growth factor signalling. The epidermal growth factor receptor (EGFR) is a member of a family of …

… Signaling pathways stimulated by growth factors and their receptor tyrosine kinases.
Growth factor binding to and dimerization of transmembrane receptors is followed by trans-…

… in this large protein family are the insulin receptor and the receptors for growth factors such
as epidermal growth factor, fibroblast growth factor and vascular endothelial growth factor. …