Toll-like receptors in immunity and inflammatory diseases: Past, present, and future

K Vijay - International immunopharmacology, 2018 - Elsevier
… and inflammatory diseasesinflammatory diseases. Thus, in the present review the current
and future importance of TLRs in immunity, their pattern of expression among various immune

NPY and receptors in immune and inflammatory diseases

J Wheway, H Herzog, F Mackay - Current topics in medicinal …, 2007 - ingentaconnect.com
immune system such as allergy and asthma. Asthma is a chronic inflammatory disease of …
Yet, despite a century of knowledge about eosinophilic infiltration in the airways, inflammation

Immunologically active autoantigens: the role of toll-like receptors in the development of chronic inflammatory disease

A Marshak-Rothstein, IR Rifkin - Annu. Rev. Immunol., 2007 - annualreviews.org
… Autoimmune diseases occur when the adaptive immune response is aberrantly directed
to host tissues. Systemic lupus erythematosus (SLE) and other related chronic inflammatory

NOD-like receptors: role in innate immunity and inflammatory disease

G Chen, MH Shaw, YG Kim… - … : Mechanisms of Disease, 2009 - annualreviews.org
… result in the activation of inflammatory signaling pathways such as nuclear … immune
receptors in both microbial defense and the pathogenesis of noninfectious, inflammatory diseases

Combinatorial roles of nuclear receptors in inflammation and immunity

CK Glass, S Ogawa - Nature Reviews Immunology, 2006 - nature.com
… It might be possible to develop new classes of small molecules for treatment of chronic
inflammatory diseases by exploiting distinct, receptor-specific mechanisms for repression of signal…

Targeting chemokine receptors in chronic inflammatory diseases: an extensive review

PJ Koelink, SA Overbeek, S Braber, P de Kruijf… - Pharmacology & …, 2012 - Elsevier
… their receptors in inflammatory diseases of the airways (asthma and COPD), the intestinal tract
(inflammatory bowel diseases)… Investigations of receptor-mediated and intracellular signal …

Toll-like receptors: promising therapeutic targets for inflammatory diseases

A Achek, D Yesudhas, S Choi - Archives of pharmacal research, 2016 - Springer
diseases. In this review, we discuss the emerging role of TLRs in the pathogenesis of
inflammatory diseases … prevention and treatment of various inflammatory diseases. Additionally, …

DAMP-sensing receptors in sterile inflammation and inflammatory diseases

T Gong, L Liu, W Jiang, R Zhou - Nature Reviews Immunology, 2020 - nature.com
… Here we focus on the receptors that sense DAMPs, in order to discuss their … inflammatory
diseases. Moreover, we consider the crosstalk between different DAMP-sensing receptors. …

Toll-like receptors in skin infections and inflammatory diseases

Y Lai, RL Gallo - … -Drug Targets (Formerly Current Drug Targets …, 2008 - ingentaconnect.com
… systems, suggest PRRs are a key component of innate immunity. Here we will focus on
describing the roles of Toll-like receptors in infections and inflammatory diseases of the skin. …

Dendritic cells, chemokine receptors and autoimmune inflammatory diseases

PD Cravens, PE Lipsky - Immunology and cell biology, 2002 - Wiley Online Library
diseases and have been identified in lesions associated with several autoimmune inflammatory
diseases. … -presenting cell (APC) of the immune system and the only APC capable of …