Fragmented hyaluronan has no alarmin function assessed in arthritis synovial fibroblast and chondrocyte cultures
M Olsson, L Bremer, C Aulin, HE Harris - Innate Immunity, 2018 - journals.sagepub.com
Hyaluronan (HA) is a large polymer and an important component of the extracellular matrix.
During homeostasis, high molecular mass HA is the predominant form, but upon …
During homeostasis, high molecular mass HA is the predominant form, but upon …
Hyaluronan (HA) fragments induce chemokine gene expression in alveolar macrophages. The role of HA size and CD44.
CM McKee, MB Penno, M Cowman… - The Journal of …, 1996 - Am Soc Clin Investig
… , but it has since been recognized as the receptor for the complex of … Molecular cloning of a
novel hyaluronan receptor that … aortic smooth muscle cells after wounding injury. The role of …
novel hyaluronan receptor that … aortic smooth muscle cells after wounding injury. The role of …
Identification of the hyaluronan receptor for endocytosis (HARE)
B Zhou, JA Weigel, LA Fauss, PH Weigel - Journal of Biological Chemistry, 2000 - ASBMB
… Rat liver sinusoidal endothelial cells (LECs) express two hyaluronan (HA) receptors, of 175
… The 97-kDa subunit was not recognized by any of the mAbs in Western blots. Based on their …
… The 97-kDa subunit was not recognized by any of the mAbs in Western blots. Based on their …
Hyaluronan up-regulates growth and invasion of trophoblasts in an autocrine manner via PI3K/AKT and MAPK/ERK1/2 pathways in early human pregnancy
R Zhu, YH Huang, Y Tao, SC Wang, C Sun, HL Piao… - Placenta, 2013 - Elsevier
Introduction As one of the key molecules in the extracellular matrix in human conceptus,
hyaluronan (HA) has been receiving particular attention. Here, we have investigated the …
hyaluronan (HA) has been receiving particular attention. Here, we have investigated the …
Lung Hyaluronasome: Involvement of Low Molecular Weight Ha (Lmw-Ha) in Innate Immunity
A Hoarau, M Polette, C Coraux - Biomolecules, 2022 - mdpi.com
… Their production is regulated by the transmembrane enzymes hyaluronan synthases (HAS). …
and waste products into the site of injury. Several important functions associated with HA …
and waste products into the site of injury. Several important functions associated with HA …
[PDF][PDF] Toll-Like Receptor 2 Dependent Signaling of Low Molecular Weight Hyaluronan Upregulates T-Helper 17 Differentiation and Promotes the Expression of …
KM Woodman - 2017 - core.ac.uk
… pattern recognition receptors … hyaluronan, a structural polysaccharide found in the extracellular
matrix. We initially hypothesized that low molecular weight hyaluronan, indicative of injury…
matrix. We initially hypothesized that low molecular weight hyaluronan, indicative of injury…
Toll-like receptor 2 (TLR2), transforming growth factor-β, hyaluronan (HA), and receptor for HA-mediated motility (RHAMM) are required for surfactant protein A …
… roles in regulation of host defense via recognition of specific pathogen-associated molecular
… after bleomycin injury, suggesting that HA is critical in macrophage recruitment to the lung ( …
… after bleomycin injury, suggesting that HA is critical in macrophage recruitment to the lung ( …
CD19, a response regulator of B lymphocytes, regulates wound healing through hyaluronan-induced TLR4 signaling
Y Iwata, A Yoshizaki, K Komura, K Shimizu… - The American journal of …, 2009 - Elsevier
… Collectively, the influence of HA on B cell functions would provide novel mechanisms
how CD19 expression affects wound healing process: under the sterile injury, increased HA …
how CD19 expression affects wound healing process: under the sterile injury, increased HA …
35kDa hyaluronan ameliorates ethanol driven loss of anti-microbial defense and intestinal barrier integrity in a TLR4-dependent manner
S Ray, E Huang, GA West, M Mrdjen, MR McMullen… - Matrix Biology, 2023 - Elsevier
… protecting the gastrointestinal tract but also other organs from alcohol-associated injury. For
instance, in murine models of ALD, liver injury is reduced by restoring C-type lectin AMPs [11…
instance, in murine models of ALD, liver injury is reduced by restoring C-type lectin AMPs [11…
Cardiac hyaluronan synthesis is critically involved in the cardiac macrophage response and promotes healing after ischemia reperfusion injury
A Petz, M Grandoch, DJ Gorski, M Abrams… - Circulation …, 2019 - Am Heart Assoc
… An interesting candidate ECM system in this regard is hyaluronan (HA). HA is a … , 13 and
autoimmune 14 diseases, it has been recognized that HA strongly affects immune responses. …
autoimmune 14 diseases, it has been recognized that HA strongly affects immune responses. …