Aerosol delivery of recombinant human DNase I: in vitro comparison of a vibrating-mesh nebulizer with a jet nebulizer
JC Johnson, JC Waldrep, J Guo, R Dhand - Respiratory care, 2008 - rc.rcjournal.com
… In previous investigations, clinical response to inhaled rhDNase was similar with jet nebulizers
… in the jet nebulizer after nebulization, so we had to resort to weighing the nebulizers to …
… in the jet nebulizer after nebulization, so we had to resort to weighing the nebulizers to …
Comparison of three jet nebulizer aerosol delivery systems used to administer recombinant human DNase I to patients with cystic fibrosis
SB Fiel, HJ Fuchs, C Johnson, I Gonda, AB Clark - Chest, 1995 - Elsevier
… in pulmonary function achieved with recombinant human DNase I (rhDNase) administered
… Acorn II nebulizer, the Hudson T Up-draft nebulizer, and the Pari LC Jet Plus nebulizer with …
… Acorn II nebulizer, the Hudson T Up-draft nebulizer, and the Pari LC Jet Plus nebulizer with …
Inhalation therapy with recombinant human deoxyribonuclease I
I Gonda - Advanced drug delivery reviews, 1996 - Elsevier
… process were ever detected when using compressed air driven jet nebulizers. Some ultrasonic
… with cystic fibrosis and the in vivo effects of recombinant human DNase I. In: Proceedings …
… with cystic fibrosis and the in vivo effects of recombinant human DNase I. In: Proceedings …
Characterization of aerosols of human recombinant deoxyribonuclease I (rhDNase) generated by jet nebulizers
D Cipolla, I Gonda, SJ Shire - Pharmaceutical research, 1994 - Springer
… Recombinant human deoxyribonuclease I (rhDNase) is a new therapeutic agent developed
… purulent sputum from the human airways. It is delivered by inhalation. Four jet nebulizers, T …
… purulent sputum from the human airways. It is delivered by inhalation. Four jet nebulizers, T …
Jet nebulising systems for recombinant human DNase I.
JC Hung, G Hambleton, M Super - Archives of Disease in …, 1994 - ncbi.nlm.nih.gov
… delivering active DNase aerosol by comparing them with two of the recommended systems
(Hudson T Updraft II nebuliser/Pulmo-aide compressor and Medic-aid Sidestream nebuliser/…
(Hudson T Updraft II nebuliser/Pulmo-aide compressor and Medic-aid Sidestream nebuliser/…
Aerosolized recombinant human DNase I for the treatment of cystic fibrosis
S Shak - Chest, 1995 - Elsevier
… fibrosis.9, 10, 11, 12 The rhDNase was administered using a simple compressed-air-driven
jet nebulizer, and increasing doses were administered by altering the duration of inhalation. …
jet nebulizer, and increasing doses were administered by altering the duration of inhalation. …
[PDF][PDF] Comparison of Three Jet Nebulizer Aerosol Delivery Systems Used to Administer Recombinant Human DNase I
C Johnson, I Gonda - CHEST, 1995 - researchgate.net
… ment in pulmonaryfunction achieved with recombinant human DNase I (rhDNase) … Acorn
II nebulizer, the Hudson T Up-draft nebulizer, and the Pari LC Jet Plus nebulizer with the Pari …
II nebulizer, the Hudson T Up-draft nebulizer, and the Pari LC Jet Plus nebulizer with the Pari …
Pharmacoeconomic review of recombinant human DNase in the management of cystic fibrosis
GS Zijlstra, C Boersma, HW Frijlink… - Expert review of …, 2004 - Taylor & Francis
… with nebulized rhDNase … jet nebulizer or electricity if an ultrasonic nebulizer is used.
Furthermore, the low efficiency is a major drawback. It has been reported that for the jet nebulizers, …
Furthermore, the low efficiency is a major drawback. It has been reported that for the jet nebulizers, …
Pharmacology, clinical efficacy and safety of recombinant human DNase in cystic fibrosis
EM Bakker, H Tiddens - Expert Review of Respiratory Medicine, 2007 - Taylor & Francis
… In general, jet nebulizers do not have these drawbacks. Two jet nebulizers were extensively
… There is no established protocol to test equivalence for alternative nebulizers. In principle, …
… There is no established protocol to test equivalence for alternative nebulizers. In principle, …
[PDF][PDF] Formulation and Aerosol Delivery of Recombinant Deoxyribonucleic Acid Derived Human Deoxyribonuclease I DC Cipolla, I. Gonda, KC Meserve, S. Weck, and …
DC Cipolla - 1994 - academia.edu
… Human DNase produced by recombinant DNA technology (rhDNase) can improve the …
We report here the formulation and aerosol delivery by jet nebulizers of rhDNase. Although the …
We report here the formulation and aerosol delivery by jet nebulizers of rhDNase. Although the …
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