Local excision after preoperative chemoradiotherapy for rectal cancer: results of a multicenter phase II clinical trial

S Pucciarelli, A De Paoli, M Guerrieri… - … of the colon & rectum, 2013 - journals.lww.com
… We therefore designed a prospective multicenter phase II study to address the impact of …
in clinically staged T3 or low-lying T2 rectal cancer patients who had a major clinical response …

Preoperative hyperthermia combined with radiochemotherapy in locally advanced rectal cancer: a phase II clinical trial

B Rau, P Wust, P Hohenberger, J Löffel… - Annals of …, 1998 - journals.lww.com
… In conclusion, this phase II study demonstrates that a trimodal therapy regimen with acceptable
toxicity can be applied safely in patients with advanced rectal carcinomas. HT was used …

Robot-assisted versus laparoscopic surgery for rectal cancer: a phase II open label prospective randomized controlled trial

MJ Kim, SC Park, JW Park, HJ Chang, DY Kim… - 2018 - journals.lww.com
… This study used a randomized, phase II, parallel design. The incompletion rate of TME for
the rectal cancer … In conclusion, robot-assisted surgery for mid- to low-lying rectal cancer was …

Preoperative radiochemotherapy in rectal cancer:: Long-term results of a phase II trial

JF Bosset, V Magnin, P Maingon, G Mantion… - International Journal of …, 2000 - Elsevier
… Preoperative chemoradiotherapy is feasible in rectal cancer patients and does not induce
unacceptable toxicity. Its potential value should be demonstrated throughout clinical trials. …

Preoperative treatment with capecitabine, bevacizumab and radiotherapy for primary locally advanced rectal cancer–a two stage phase II clinical trial

…, Austrian Breast and Colorectal Cancer Study … - Radiotherapy and …, 2012 - Elsevier
… In recent years our study group designed clinical trials to improve the efficacy in terms of
local recurrence and prevention of metastases in rectal cancer. In the R02 study [26] the …

Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by …

A Dewdney, D Cunningham, J Tabernero… - Journal of Clinical …, 2012 - ascopubs.org
… ), and OS in metastatic colorectal cancer 27,28 and survival … poor prognosis rectal cancer in
a single-arm phase II trial (EXPERT… (EGFR) therapy in metastatic colorectal cancer, 31,32 the …

Effect of laparoscopic-assisted resection vs open resection of stage II or III rectal cancer on pathologic outcomes: the ACOSOG Z6051 randomized clinical trial

J Fleshman, M Branda, DJ Sargent, AM Boller… - Jama, 2015 - jamanetwork.com
… In this multicenter, prospective, randomized, controlled trial of patients with stage II or III
rectal cancer at or below 12 cm above the anal verge, all of whom underwent neoadjuvant …

Multicenter phase II trial of chemoradiation with oxaliplatin for rectal cancer

C Rödel, T Liersch, RM Hermann, D Arnold… - Journal of Clinical …, 2006 - ascopubs.org
… One hundred ten patients with T3/T4 or N+ rectal cancer were entered onto the trial in 11
investigator sites and received preoperative RT (50.4 Gy in 28 fractions). Capecitabine was …

Phase II clinical trial to evaluate the efficacy of transanal endoscopic total mesorectal excision for rectal cancer

SC Park, DK Sohn, MJ Kim, HJ Chang… - … the Colon & Rectum, 2018 - journals.lww.com
… This phase II prospective study was conducted to evaluate … rectal cancer based on the
results of our previous pilot study showing the safety and feasibility of this procedure. In this study, …

… Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer …

…, K Avila, J Garcia-Aguilar, Rectal Cancer Consortium - BMC cancer, 2015 - Springer
phase II study investigates the efficacy of total neoadjuvant therapy (TNT) and selective
non-operative management (NOM) in LARC. Patients with MRI-staged Stage II or III rectal cancer