ROS, redox regulation, and anticancer therapy

MP Bansal - Redox regulation and therapeutic approaches in …, 2023 - Springer
… , redox signaling targeting as anticancer therapy, introduces using agents to inactivate
various redox regulatory … Application of miRNA as targeting therapy has also been explained. …

Redox‐active metal complexes for anticancer therapy

P Zhang, PJ Sadler - European Journal of Inorganic Chemistry, 2017 - Wiley Online Library
… for anticancer therapy involving redox-activated prodrug strategies and redox modulation. …
Here we describe the potential role of redox modulation in the mechanism of action of metal …

Reactive oxygen species in cancer biology and anticancer therapy

Y Yang, S Karakhanova, J Werner… - Current medicinal …, 2013 - ingentaconnect.com
… ROSelevating and ROS-depleting anticancer strategies and their mechanisms are … therapy
choice depends on a complete understanding of cancer cell redox state, namely, the “redox

Cellular redox pathways as a therapeutic target in the treatment of cancer

AJ Montero, J Jassem - Drugs, 2011 - Springer
… In this article we review anticancer drugs currently in development that target cellular … In
this article, the role of redox regulation in carcinogenesis and its potential as a therapeutic target …

Mitochondrial redox hubs as promising targets for anticancer therapy

L Ippolito, E Giannoni, P Chiarugi, M Parri - Frontiers in oncology, 2020 - frontiersin.org
… These are the reasons MTHFD2 may symbolize a likely mitochondrial redox anticancer
therapeutic agent. In a murine model of AML, blocking MTHFD2 by silencing with shRNA the …

Understanding of ROS‐inducing strategy in anticancer therapy

SJ Kim, HS Kim, YR Seo - Oxidative medicine and cellular …, 2019 - Wiley Online Library
… Recently, anticancer therapies that induce … redox homeostasis and causes severe damage
in cancer cells. In this review, we describe ROS-inducing cancer therapy and the anticancer

Increased oxidative stress as a selective anticancer therapy

J Liu, Z Wang - Oxidative medicine and cellular longevity, 2015 - Wiley Online Library
… that increased oxidative stress by exogenous ROS generation therapy has an effect on
selectively killing … of redox regulation in CSCs and the pivotal role of ROS in anticancer treatment. …

Targeting of the intracellular redox balance by metal complexes towards anticancer therapy

MI Murillo, C Gaiddon, R Le Lagadec - Frontiers in chemistry, 2022 - frontiersin.org
… published every year on the anticancer activity of transition metal complexes, in … redox
processes in cancer metabolic pathways, and how tumor development may be hindered by redox

Redox regulation and its emerging roles in cancer treatment

H Zhang, Z Mao, Y Kang, W Zhang, L Mei… - Coordination Chemistry …, 2023 - Elsevier
… to enhance the ROS regulation efficient. Finally, we illustrate the prospects of the redox
regulating nanotechnology, including combined/synergistic anticancer therapies and challenges …

Redox regulation in cancer: a double‐edged sword with therapeutic potential

A Acharya, I Das, D Chandhok… - Oxidative medicine and …, 2010 - Wiley Online Library
… intracellular redox status and … Therapeutic inhibition of the OPP and/or the GSH defense
system might increase the sensitivity of gastric and colon cancer cells to anti-cancer therapy.…