Gastro‐oesophageal reflux disease–pathophysiological issues of clinical relevance

R Penagini, S Carmagnola… - Alimentary pharmacology …, 2002 - Wiley Online Library
… The clinical relevance of Helicobacter pylori infection and of … give definite answers on the
clinical relevance of the interaction … little relevance to what occurs during single reflux episodes. …

[HTML][HTML] Historical perspective of gastroesophageal reflux disease clinical treatment

S Zaterka, SB Marion, F Roveda, MA Perrotti… - Arquivos de …, 2019 - SciELO Brasil
reflux disease (GERD) is one of the most prevalent gastrointestinal conditions, resulting
in significant impairment in patients’ health-related quality of life and also relevant medical …

[HTML][HTML] Gastroesophageal reflux disease: a practical approach

G Domingues, JPP de Moraes-Filho - Arquivos de Gastroenterologia, 2021 - SciELO Brasil
Relevant clinical findings are … Clinical trial: the effects of the proton pump inhibitor
dexlanzoprazole MR on daytime and nighttime heartburn in patients with non-erosive reflux disease. …

Symptomatic reflux disease: the present, the past and the future

G Boeckxstaens, HB El-Serag, AJPM Smout… - Gut, 2014 - gut.bmj.com
… PPI therapy also provides enhanced inhibition of nocturnal acid secretion, but this effect
has not been shown clinically relevant and is subject to tachyphylaxis within a few weeks.76 …

Nonerosive reflux disease: clinical concepts

CP Gyawali, DE Azagury, WW Chan… - Annals of the New …, 2018 - Wiley Online Library
reflux monitoring is performed “on” versus “off” therapy is crucial in obtaining clinically relevant
… taking into consideration the clinical presentation and pretest evidence for reflux. Off-PPI …

Relevance of histology in the diagnosis of reflux esophagitis

M Tripathi, CJ Streutker… - Annals of the New York …, 2018 - Wiley Online Library
Reflux esophagitis is an important clinical diagnosis; however, the histologic findings …
reflux disease (GERD) of the esophagus are discussed, along with the issues relating to clinical

Clinical relevance of esophageal and gastric pH measurements in patients with gastro-esophageal reflux disease (GERD)

AJ DiMarino Jr, S Cohen - Current medical research and opinion, 2005 - Taylor & Francis
… is considered clinically relevant since heartburn occurs when … of six pH criteria: cumulative
reflux time, expressed as the … of reflux episodes, expressed as the number of reflux episodes …

the clinical relevance of transient lower oesophageal sphincter relaxations in gastro‐oesophageal reflux disease

BF Kessing, JM Conchillo… - Alimentary …, 2011 - Wiley Online Library
… most reflux episodes occur during TLOSRs and therefore play a key role in gastro-oesophageal
reflux disease … As TLOSRs play a key role in gastro-oesophageal reflux disease (GERD), …

Advances in the diagnosis and management of gastroesophageal reflux disease

DA Katzka, PJ Kahrilas - Bmj, 2020 - bmj.com
… Gastroesophageal reflux disease (GERD) is a multifaceted … reflux that impart morbidity,
mainly through troublesome symptoms. Major GERD phenotypes are non-erosive reflux disease, …

Gastroesophageal reflux disease: clinical manifestations

JL Williams - Gastroenterology Nursing, 2003 - journals.lww.com
… The Los Angeles Classification is a widely used and clinically relevant system to grade the
severity of erosive esophagitis at endoscopy. The goals of treatment are to achieve complete …